Ming-Tsung Lai
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Explore the profile of Ming-Tsung Lai including associated specialties, affiliations and a list of published articles.
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Articles
37
Citations
511
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Recent Articles
1.
Chung Y, Chen S, Huang C, Liu W, Lai M, Kao T, et al.
Pharmaceuticals (Basel)
. 2024 Jan;
17(1).
PMID: 38256960
The use of tocilizumab against the interleukin-6 receptor (IL-6R) has been demonstrated as inhibiting the progression of diverse cancers in vitro and in vivo. Nonetheless, evidence regarding the anti-tumor effects...
2.
Wang E, Chen I, Kuo B, Yu C, Lai M, Lin J, et al.
Biomolecules
. 2022 Dec;
12(12).
PMID: 36551290
Cytoskeleton proteins have been long recognized as structural proteins that provide the necessary mechanical architecture for cell development and tissue homeostasis. With the completion of the cancer genome project, scientists...
3.
Chang C, Yang L, Tse J, Lo L, Tseng C, Sun L, et al.
PLoS One
. 2022 Jul;
17(7):e0271616.
PMID: 35901079
Endometriosis is a hormone-associated disease which has been considered as the precursor for certain types of ovarian cancer. In recent years, emerging evidence demonstrated potent roles of lncRNA in regulating...
4.
Chang C, Chiang A, Yan M, Lai M, Su Y, Huang H, et al.
Biomedicines
. 2022 Jan;
10(1).
PMID: 35052864
Ribosome biogenesis is a cellular process critical for protein homeostasis during cell growth and multiplication. Our previous study confirmed up-regulation of ribosome biogenesis during endometriosis progression and malignant transition, thus...
5.
Chang C, Chiang A, Lai M, Yan M, Tseng C, Lo L, et al.
Biomedicines
. 2022 Jan;
10(1).
PMID: 35052854
Infection-induced chronic inflammation is common in patients with endometriosis. Although microbial communities in the reproductive tracts of patients have been reported, little was known about their dynamic profiles during disease...
6.
Chang C, Tseng C, Lai M, Chiang A, Lo L, Chen C, et al.
PLoS One
. 2021 Mar;
16(3):e0248168.
PMID: 33667269
HOTAIR is a well-known long non-coding RNA (lncRNA) involved in various cellular signaling, whereas its functional impacts on endometriosis development are still largely unknown. To this end, six potential functional...
7.
Korla P, Chen C, Gracilla D, Lai M, Chen C, Chen H, et al.
Theranostics
. 2020 Nov;
10(26):12026-12043.
PMID: 33204327
Cell-cell interaction in skin homeostasis is tightly controlled by adherens junctions (AJs). Alterations in such regulation lead to melanoma development. However, mutations in AJs and their functional consequences are still...
8.
Gracilla D, Korla P, Lai M, Chiang A, Liou W, Sheu J
Mol Oncol
. 2020 Sep;
14(12):3065-3082.
PMID: 32979859
Cadherin-mediated cell-cell contacts regulated by intracellular binders play critical roles in tissue homeostasis and tumorigenesis. Here, we screened mutational profiles of 312 annotated genes involved in cadherin binding in human...
9.
Yu C, Li C, Chen I, Lai M, Lin Z, Korla P, et al.
J Pathol
. 2019 Apr;
248(4):476-487.
PMID: 30945298
The objective of this study was to characterize the oncogenic actions of a recently identified cancer-associated gene YWHAZ (also named as 14-3-3 ζ/δ) in urothelial carcinomas of the urinary bladder...
10.
Tsai F, Lai M, Cheng J, Chao S, Korla P, Chen H, et al.
Oncogene
. 2019 Mar;
38(26):5113-5126.
PMID: 30867567
Keratin intermediate filament (IF) is one component of cellular architectures, which provides necessary mechanical support to conquer environmental stresses. Recent findings reveal its involvement in mechano-transduction and the associated stem...