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Minetaka Isomura

Explore the profile of Minetaka Isomura including associated specialties, affiliations and a list of published articles. Areas
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Articles 3
Citations 43
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Recent Articles
1.
Kaburagi Y, Kira K, Yahata K, Iso K, Sato Y, Matsuura F, et al.
Org Lett . 2024 Jan; 26(14):2837-2842. PMID: 38252895
E7130 is a novel drug candidate with an exceedingly complex chemical structure of the halichondrin class, discovered by a total synthesis approach through joint research between the Kishi group at...
2.
Kawano S, Ito K, Yahata K, Kira K, Abe T, Akagi T, et al.
Sci Rep . 2019 Jun; 9(1):8656. PMID: 31209263
Despite their outstanding antitumour activity in mice, the limited supply from the natural sources has prevented drug discovery/development based on intact halichondrins. We achieved a total synthesis of C52-halichondrin-B amine...
3.
Wilde N, Isomura M, Mendoza A, Baran P
J Am Chem Soc . 2014 Mar; 136(13):4909-12. PMID: 24625050
The first successful effort to replicate the beginning of the Taxol oxidase phase in the laboratory is reported, culminating in the total synthesis of taxuyunnanine D, itself a natural product....