Mindy C Kohlhagen
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Explore the profile of Mindy C Kohlhagen including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
200
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Recent Articles
11.
Kohlhagen M, Mills J, Willrich M, Dasari S, Dispenzieri A, Murray D
Clin Biochem
. 2021 Mar;
92:61-66.
PMID: 33691184
Objective: To explore the possibility of using a combination of a rapid MALDI-TOF-MS method (Mass-Fix) in conjunction with higher resolution LC-ESI-QTOF-MS (miRAMM) measurements to discriminate the IgG kappa M-protein from...
12.
Mellors P, Dasari S, Kohlhagen M, Kourelis T, Go R, Muchtar E, et al.
Blood Cancer J
. 2021 Mar;
11(3):50.
PMID: 33664227
Immunoenrichment-based matrix assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS), termed MASS-FIX, offers several advantages over immunofixation for the detection and isotyping of serum monoclonal protein, including superior sensitivity and...
13.
Fung A, Kohlhagen M, DeMarco M, Mills J
Clin Chem
. 2019 Sep;
65(9):1084-1088.
PMID: 31481352
No abstract available.
14.
Sepiashvili L, Kohlhagen M, Snyder M, Willrich M, Mills J, Dispenzieri A, et al.
Clin Chem
. 2019 Jun;
65(8):1015-1022.
PMID: 31171529
Background: Free light chain (FLC) quantification is the most analytically sensitive blood-based method commercially available to diagnose and monitor patients with plasma cell disorders (PCDs). However, instead of directly detecting...
15.
Mills J, Kohlhagen M, Willrich M, Kourelis T, Dispenzieri A, Murray D
Blood
. 2018 Jun;
132(6):670-672.
PMID: 29891533
No abstract available.
16.
Milani P, Murray D, Barnidge D, Kohlhagen M, Mills J, Merlini G, et al.
Am J Hematol
. 2017 Apr;
92(8):772-779.
PMID: 28439985
The detection and quantification of monoclonal-proteins (M-proteins) are necessary for the diagnosis and evaluation of response in plasma cell dyscrasias. Immunoglobulin enrichment-coupled with matrix-assisted laser desorption ionization time-of-flight mass-spectrometry (MASS-FIX)...
17.
Mills J, Kohlhagen M, Dasari S, Vanderboom P, Kyle R, Katzmann J, et al.
Clin Chem
. 2016 Aug;
62(10):1334-44.
PMID: 27540026
Background: Electrophoretic separation of serum and urine proteins has played a central role in diagnosing and monitoring plasma cell disorders. Despite limitations in resolution and analytical sensitivity, plus the necessity...
18.
Kohlhagen M, Barnidge D, Mills J, Stoner J, Gurtner K, Liptac A, et al.
Clin Chem
. 2016 Aug;
62(10):1345-52.
PMID: 27515443
Background: Current recommendations for screening for monoclonal gammopathies include serum protein electrophoresis (PEL), imunofixation electrophoresis (IFE), and free light chain (FLC) ratios to identify or rule out an M-protein. The...
19.
Barnidge D, Kohlhagen M, Zheng S, Willrich M, Katzmann J, Pittock S, et al.
J Neuroimmunol
. 2015 Nov;
288:123-6.
PMID: 26531705
Our group has previously shown that mass spectrometry can be used to detect and quantify monoclonal and polyclonal immunoglobulin light chains in serum and urine from patients with monoclonal gammopathies...
20.
Katzmann J, Willrich M, Kohlhagen M, Kyle R, Murray D, Snyder M, et al.
Clin Chem
. 2014 Dec;
61(2):360-7.
PMID: 25451866
Background: The use of electrophoresis to monitor monoclonal immunoglobulins migrating in the β fraction may be difficult because of their comigration with transferrin and complement proteins. Methods: Immunoassays specific for...