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Min Suk Han

Explore the profile of Min Suk Han including associated specialties, affiliations and a list of published articles. Areas
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Articles 5
Citations 225
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Recent Articles
1.
Wiggins-Dohlvik K, Stagg H, Han M, Alluri H, Oakley R, Anasooya Shaji C, et al.
Shock . 2015 Dec; 45(6):626-33. PMID: 26717103
Introduction: Lipopolysaccharide (LPS) is known to induce vascular derangements. The pathophysiology involved therein is unknown, but matrix metalloproteinases (MMPs) may be an important mediator. We hypothesized that in vitro LPS...
2.
Wiggins-Dohlvik K, Oakley R, Han M, Stagg H, Alluri H, Shaji C, et al.
Am J Surg . 2015 Nov; 211(1):197-205. PMID: 26601648
Background: Burns induce microvascular hyperpermeability. We hypothesize that this occurs partly through an imbalance between matrix metalloproteinases (MMPs) and endogenous MMP inhibitors such as tissue inhibitors of metalloproteinases (TIMPs), and...
3.
Wiggins-Dohlvik K, Han M, Stagg H, Alluri H, Anasooya Shaji C, Oakley R, et al.
J Trauma Acute Care Surg . 2014 Jul; 77(6):899-905. PMID: 25051382
Background: Burns induce systemic inflammatory reactions and vascular hyperpermeability. Breakdown of endothelial cell adherens junctions is integral in this process, and reactive oxygen species (ROS) and proteolytic enzymes such as...
4.
Hetrick B, Han M, Helgeson L, Nolen B
Chem Biol . 2013 Apr; 20(5):701-12. PMID: 23623350
Actin-related protein 2/3 (Arp2/3) complex is a seven-subunit assembly that nucleates branched actin filaments. Small molecule inhibitors CK-666 and CK-869 bind to Arp2/3 complex and inhibit nucleation, but their modes...
5.
Baggett A, Cournia Z, Han M, Patargias G, Glass A, Liu S, et al.
ChemMedChem . 2012 May; 7(7):1286-94. PMID: 22623398
CK-666 (1) is a recently discovered small-molecule inhibitor of the actin-related protein 2/3 (Arp2/3) complex, a key actin cytoskeleton regulator with roles in bacterial pathogenesis and cancer cell motility. Although...