Min Jie Alvin Tan
Overview
Explore the profile of Min Jie Alvin Tan including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
441
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0
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Recent Articles
1.
Cheng C, Tan M, Chan K, Choy M, Roman N, Arnold D, et al.
ACS Infect Dis
. 2024 May;
10(6):2047-2062.
PMID: 38811007
Dengue virus (DENV) nonstructural protein 5 (NS5), consisting of methyltransferase and RNA-dependent RNA polymerase (RdRp) domains, is critical for viral RNA synthesis within endoplasmic reticulum-derived replication complexes in the cytoplasm....
2.
Bifani A, Chan K, Borrenberghs D, Tan M, Phoo W, Watanabe S, et al.
Antiviral Res
. 2023 Jan;
210:105517.
PMID: 36592668
Flaviviruses are vector-borne pathogens capable of causing devastating human diseases. The re-emergence of Zika in 2016 notoriously led to a widescale epidemic in the Americas. New daunting evidence suggests that...
3.
Wang S, Chan K, Tan M, Flory C, Luo D, Lescar J, et al.
RNA
. 2021 Nov;
28(2):177-193.
PMID: 34759006
The commitment to replicate the RNA genome of flaviviruses without a primer involves RNA-protein interactions that have been shown to include the recognition of the stem-loop A (SLA) in the...
4.
Cheng C, Tan M, Chan K, Watanabe S, Wang S, Choy M, et al.
ACS Infect Dis
. 2021 Nov;
7(12):3277-3291.
PMID: 34735113
Dengue virus (DENV) non-structural protein 5 (NS5) is critical for viral RNA synthesis within endoplasmic reticulum (ER)-derived replication complexes in the cytoplasm; however a proportion of NS5 is known to...
5.
Tan M, Brown N, Chan K, Jin J, Kong S, Vasudevan S
J Gen Virol
. 2020 Jun;
101(9):941-953.
PMID: 32589122
The dengue virus (DENV) replication complex is made up of its non-structural (NS) proteins and yet-to-be identified host proteins, but the molecular interactions between these proteins are not fully elucidated....
6.
Tan M, Chan K, Ng I, Kong S, Gwee C, Watanabe S, et al.
Cells
. 2019 Nov;
8(12).
PMID: 31779251
The Zika virus (ZIKV) non-structural protein 5 (NS5) plays multiple viral and cellular roles during infection, with its primary role in virus RNA replication taking place in the cytoplasm. However,...
7.
Ng I, Chan K, Tan M, Gwee C, Smith K, Jeffress S, et al.
ACS Infect Dis
. 2019 Mar;
5(6):932-948.
PMID: 30848123
The Zika virus (ZIKV) epidemic in the Americas was alarming because of its link with microcephaly in neonates and Guillain-Barré syndrome in adults. The unusual pathologies induced by ZIKV infection...
8.
Bentley P, Tan M, McBride A, White E, Howley P
J Virol
. 2018 Jun;
92(15).
PMID: 29848583
The papillomavirus E2 protein executes numerous essential functions related to viral transcription, replication of viral DNA, and viral genome maintenance. Because E2 lacks enzymatic activity, many of these functions are...
9.
Chang D, Hoang L, Mohamed Naim A, Dong H, Schreiber M, Hibberd M, et al.
Virology
. 2016 Oct;
499:259-266.
PMID: 27716465
Dengue virus (DENV) is the most prevalent mosquito-borne virus pathogen in humans. There is currently no antiviral therapeutic or widely available vaccine against dengue infection. The DENV RNA genome is...
10.
Lyi S, Tan M, Parrish C
Virology
. 2014 Jun;
456-457:342-52.
PMID: 24889253
Cell infection by parvoviruses requires that capsids be delivered from outside the cell to the cytoplasm, followed by genome trafficking to the nucleus. Here we microinject capsids into cells that...