Millard Jayne
Overview
Explore the profile of Millard Jayne including associated specialties, affiliations and a list of published articles.
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26
Citations
2349
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Recent Articles
1.
Fowler J, Logan J, Volkow N, Shumay E, McCall-Perez F, Jayne M, et al.
Neuropsychopharmacology
. 2014 Sep;
40(3):650-7.
PMID: 25249059
Selegiline (L-deprenyl) is a selective, irreversible inhibitor of monoamine oxidase B (MAO-B) at the conventional dose (10 mg/day oral) that is used in the treatment of Parkinson's disease. However, controlled...
2.
Volkow N, Wang G, Telang F, Fowler J, Alexoff D, Logan J, et al.
Proc Natl Acad Sci U S A
. 2014 Jul;
111(30):E3149-56.
PMID: 25024177
Moves to legalize marijuana highlight the urgency to investigate effects of chronic marijuana in the human brain. Here, we challenged 48 participants (24 controls and 24 marijuana abusers) with methylphenidate...
3.
Wang G, Volkow N, Wigal T, Kollins S, Newcorn J, Telang F, et al.
PLoS One
. 2013 May;
8(5):e63023.
PMID: 23696790
Objective: Brain dopamine dysfunction in attention deficit/hyperactivity disorder (ADHD) could explain why stimulant medications, which increase dopamine signaling, are therapeutically beneficial. However while the acute increases in dopamine induced by...
4.
Biegon A, Kim S, Alexoff D, Jayne M, Carter P, Hubbard B, et al.
Synapse
. 2010 Sep;
64(11):801-7.
PMID: 20842717
Aromatase catalyzes the last step in estrogen biosynthesis. Brain aromatase is involved in diverse neurophysiological and behavioral functions including sexual behavior, aggression, cognition, and neuroprotection. Using positron emission tomography (PET)...
5.
Volkow N, Wang G, Tomasi D, Telang F, Fowler J, Pradhan K, et al.
PLoS One
. 2010 Jul;
5(7):e11509.
PMID: 20634975
Dopamine (phasic release) is implicated in conditioned responses. Imaging studies in cocaine abusers show decreases in striatal dopamine levels, which we hypothesize may enhance conditioned responses since tonic dopamine levels...
6.
Volkow N, Tomasi D, Wang G, Fowler J, Telang F, Wang R, et al.
Neuroimage
. 2010 Feb;
51(2):623-8.
PMID: 20156571
Echo planar imaging (EPI), the gold standard technique for functional MRI (fMRI), is based on fast magnetic field gradient switching. These time-varying magnetic fields induce electric (E) fields in the...
7.
Volkow N, Fowler J, Wang G, Telang F, Logan J, Jayne M, et al.
Neuroimage
. 2009 Nov;
49(3):2536-43.
PMID: 19913102
Loss of control over drug taking is considered a hallmark of addiction and is critical in relapse. Dysfunction of frontal brain regions involved with inhibitory control may underlie this behavior....
8.
Fowler J, Logan J, Azzaro A, Fielding R, Zhu W, Poshusta A, et al.
Neuropsychopharmacology
. 2009 Nov;
35(3):623-31.
PMID: 19890267
Reversible inhibitors of monoamine oxidase-A (RIMA) inhibit the breakdown of three major neurotransmitters, serotonin, norepinephrine and dopamine, offering a multi-neurotransmitter strategy for the treatment of depression. CX157 (3-fluoro-7-(2,2,2-trifluoroethoxy)phenoxathiin-10,10-dioxide) is a...
9.
Volkow N, Tomasi D, Wang G, Telang F, Fowler J, Wang R, et al.
Neuroimage
. 2009 Apr;
45(4):1232-40.
PMID: 19349237
Sleep deprivation interferes with cognitive performance but the mechanisms are poorly understood. We recently reported that one night of sleep deprivation increased dopamine in striatum (measured with [(11)C]raclopride, a PET...
10.
Volkow N, Fowler J, Logan J, Alexoff D, Zhu W, Telang F, et al.
JAMA
. 2009 Mar;
301(11):1148-54.
PMID: 19293415
Context: Modafinil, a wake-promoting drug used to treat narcolepsy, is increasingly being used as a cognitive enhancer. Although initially launched as distinct from stimulants that increase extracellular dopamine by targeting...