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Milko Velarde

Explore the profile of Milko Velarde including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 77
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Recent Articles
1.
Macieira S, Zhang J, Velarde M, Buckel W, Messerschmidt A
Biol Chem . 2009 Oct; 390(12):1251-63. PMID: 19804364
4-Hydroxybutyrate CoA-transferases (4-HB-CoAT) takes part in the fermentation of 4-aminobutyrate to ammonia, acetate, and butyrate in anaerobic bacteria such as Clostridium aminobutyricum and Porphyromonas gingivalis or facultative anaerobic bacteria such...
2.
Velarde M, Macieira S, Hilberg M, Broker G, Tu S, Golding B, et al.
J Mol Biol . 2009 Jun; 391(3):609-20. PMID: 19559030
3-Methylitaconate-Delta-isomerase (Mii) participates in the nicotinate fermentation pathway of the anaerobic soil bacterium Eubacterium barkeri (order Clostridiales) by catalyzing the reversible conversion of (R)-3-methylitaconate (2-methylene-3-methylsuccinate) to 2,3-dimethylmaleate. The enzyme is...
3.
Mendoza-Barbera E, Corral-Rodriguez M, Soares-Schanoski A, Velarde M, Macieira S, Messerschmidt A, et al.
Biochem Biophys Res Commun . 2009 Jan; 380(1):183-7. PMID: 19167362
Homotypic interactions of death domains (DD) mediate complex formation between MyD88 and IL-1 receptor-associated kinases (IRAKs). A truncated splice variant of MyD88, MyD88s, cannot recruit IRAK-4 and fails to elicit...
4.
Velarde M, Huber R, Yanagisawa S, Dennison C, Messerschmidt A
Biochemistry . 2007 Aug; 46(35):9981-91. PMID: 17685636
Atomic resolution structures of the pseudoazurin (PAZ) variant into which the shorter ligand-containing loop of amicyanin (AMI) is introduced have been determined. The mutated loop adopts a different conformation in...
5.
Messerschmidt A, Macieira S, Velarde M, Badeker M, Benda C, Jestel A, et al.
J Mol Biol . 2005 Aug; 352(4):918-31. PMID: 16125198
Atypical protein kinases C (aPKCs) play critical roles in signaling pathways that control cell growth, differentiation and survival. Therefore, they constitute attractive targets for the development of novel therapeutics against...
6.
Koch M, Velarde M, Harrison M, Echt S, Fischer M, Messerschmidt A, et al.
J Am Chem Soc . 2005 Jan; 127(1):158-66. PMID: 15631465
Umecyanin (UMC) is a type 1 copper-containing protein which originates from horseradish roots and belongs to the stellacyanin subclass of the phytocyanins, a ubiquitous family of plant cupredoxins. The crystal...