Mikita Suyama
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Explore the profile of Mikita Suyama including associated specialties, affiliations and a list of published articles.
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100
Citations
8142
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Recent Articles
1.
Yokoi N, Adachi N, Hirokoji T, Nakano K, Yoshihara M, Shigenaka S, et al.
DNA Res
. 2025 Mar;
PMID: 40036227
Type 2 diabetes is a multifactorial disease caused by insulin resistance and impaired insulin secretion from pancreatic β-cells, but the precise mechanisms remain to be elucidated. To identify primary genetic...
2.
Takao T, Matsui A, Kikutake C, Kan-O K, Inoue A, Suyama M, et al.
Nat Commun
. 2025 Jan;
16(1):631.
PMID: 39805834
The root of asthma can be linked to early life, with prenatal environments influencing risk. We investigate the effects of maternal asthma on the offspring's lungs during fetal and adult...
3.
Haratake N, Ozawa H, Morimoto Y, Yamashita N, Daimon T, Bhattacharya A, et al.
J Thorac Oncol
. 2024 Dec;
20(3):399.
PMID: 39692639
No abstract available.
4.
Toh H, Okae H, Shirane K, Sato T, Hamada H, Kikutake C, et al.
BMC Genomics
. 2024 Nov;
25(1):1050.
PMID: 39506688
Background: The placenta is essential for nutrient exchange and hormone production between the mother and the developing fetus and serves as an invaluable model for epigenetic research. Most epigenetic studies...
5.
Qu Z, Sakaguchi N, Kikutake C, Suyama M
FEBS Open Bio
. 2024 Jul;
14(10):1682-1690.
PMID: 39085971
The search for genetic variants that act as causative factors in human diseases by disrupting the normal splicing process has primarily focused on single nucleotide variants (SNVs). It is worth...
6.
Wakasa T, Nonaka K, Harada A, Ohkawa Y, Kikutake C, Suyama M, et al.
Cell Death Discov
. 2024 Jul;
10(1):307.
PMID: 38956056
The fluorinated thymidine analog trifluridine (FTD) is a chemotherapeutic drug commonly used to treat cancer; however, the mechanism by which FTD induces cytotoxicity is not fully understood. In addition, the...
7.
Deguchi Y, Kikutake C, Suyama M
Sci Rep
. 2024 Jun;
14(1):14158.
PMID: 38898123
Genome analysis in cancer has focused mainly on elucidating the function and regulatory mechanisms of genes that exhibit differential expression or mutation in cancer samples compared to normal samples. Recently,...
8.
Shibata S, Endo S, Nagai L, H Kobayashi E, Oike A, Kobayashi N, et al.
Sci Adv
. 2024 Feb;
10(8):eadi4819.
PMID: 38394208
The initiation of human pregnancy is marked by the implantation of an embryo into the uterine environment; however, the underlying mechanisms remain largely elusive. To address this knowledge gap, we...
9.
Shao R, Suzuki T, Suyama M, Tsukada Y
BMC Genomics
. 2024 Feb;
25(1):143.
PMID: 38317092
Background: Histone acetylation, which is regulated by histone acetyltransferases (HATs) and histone deacetylases (HDACs), plays a crucial role in the control of gene expression. HDAC inhibitors (HDACi) have shown potential...
10.
Shimizu T, Oike A, H Kobayashi E, Sekiya A, Kobayashi N, Shibata S, et al.
Proc Natl Acad Sci U S A
. 2023 Dec;
120(51):e2311372120.
PMID: 38085778
The placenta serves as the interface between the mother and fetus, facilitating the exchange of gases and nutrients between their separate blood circulation systems. Trophoblasts in the placenta play a...