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Mikhail Shepelev

Explore the profile of Mikhail Shepelev including associated specialties, affiliations and a list of published articles. Areas
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Articles 5
Citations 130
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Recent Articles
1.
Kruglova N, Shepelev M
Biomedicines . 2024 Jan; 12(1). PMID: 38255224
T lymphocytes represent a promising target for genome editing. They are primarily modified to recognize and kill tumor cells or to withstand HIV infection. In most studies, T cell genome...
2.
Klinkovskij A, Shepelev M, Isaakyan Y, Aniskin D, Ulasov I
Biomedicines . 2023 Dec; 11(12). PMID: 38137554
The rate of neurodegenerative disorders (NDDs) is rising rapidly as the world's population ages. Conditions such as Alzheimer's disease (AD), Parkinson's disease (PD), and dementia are becoming more prevalent and...
3.
Canoy R, Shmakova A, Karpukhina A, Shepelev M, Germini D, Vassetzky Y
Cancers (Basel) . 2022 Oct; 14(20). PMID: 36291894
Chromosomal translocations are products of the illegitimate repair of DNA double-strand breaks (DSBs). Their formation can bring about significant structural and molecular changes in the cell that can be physiologically...
4.
Maslennikova A, Kruglova N, Kalinichenko S, Komkov D, Shepelev M, Golubev D, et al.
mBio . 2022 Jan; 13(1):e0358921. PMID: 35073736
Previous studies suggest that short peptides from the heptad repeat 2 (HR2) domain of gp41 expressed on the cell surface are more potent inhibitors of HIV-1 entry than soluble analogs....
5.
Hofmann C, Shepelev M, Chernoff J
J Cell Sci . 2004 Aug; 117(Pt 19):4343-54. PMID: 15331659
p21-activated kinases (Paks) are a highly conserved family of enzymes that bind to and are activated by small GTPases of the Cdc42 and Rac families. With the notable exception of...