Mike M Sathekge
Overview
Explore the profile of Mike M Sathekge including associated specialties, affiliations and a list of published articles.
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Articles
89
Citations
662
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Recent Articles
1.
Mokoala K, Sathekge M
Semin Nucl Med
. 2024 Nov;
54(6):827-844.
PMID: 39510855
Hypoxia plays a critical role in tumor biology, influencing cancer progression, treatment resistance, and patient prognosis. While 18-Fluorine fluoredeoxyglucose ([18F]F-FDG) PET imaging has been the standard for metabolic assessment, its...
2.
Abdel-Wahab M, Giammarile F, Carrara M, Paez D, Hricak H, Ayati N, et al.
Lancet Oncol
. 2024 Oct;
25(11):e545-e580.
PMID: 39362232
Following on from the 2015 Lancet Oncology Commission on expanding global access to radiotherapy, Radiotherapy and theranostics: a Lancet Oncology Commission was created to assess the access and availability of...
3.
Koatale P, Welling M, Mdanda S, Mdlophane A, Takyi-Williams J, Durandt C, et al.
Pharmaceuticals (Basel)
. 2024 Sep;
17(9).
PMID: 39338315
The ability of bacteria to recycle exogenous amino acid-based peptides and amino sugars for peptidoglycan biosynthesis was extensively investigated using optical imaging. In particular, fluorescent AeK-NBD was effectively utilized to...
4.
Eigner S, Kleynhans J, Beckford Vera D, Sathekge M, Henke K, Ebenhan T
Sci Rep
. 2024 Aug;
14(1):19250.
PMID: 39164329
Radiolabelled puromycin analogues will allow the quantification of protein synthesis through nuclear medicine-based imaging. A particularly useful application could be the non-invasive longitudinal visualisation of mycobacterial activity through direct quantification...
5.
Kairemo K, Kgatle M, Bruchertseifer F, Morgernstern A, Sathekge M
Ann Transl Med
. 2024 Aug;
12(4):67.
PMID: 39118950
The first alpha emitting radiopharmaceutical, RaCl, radium dichloride, was approved 10 years ago into the clinical armament of treating bone metastases in metastatic castration-resistant prostate cancer (mCRPC). In addition to...
6.
Ndlovu H, Lawal I, Mdanda S, Kgatle M, Mokoala K, Al-Ibraheem A, et al.
J Clin Med
. 2024 Jun;
13(12).
PMID: 38929955
Including poly(ADP-ribose) polymerase (PARP) inhibitors in managing patients with inoperable tumors has significantly improved outcomes. The PARP inhibitors hamper single-strand deoxyribonucleic acid (DNA) repair by trapping poly(ADP-ribose)polymerase (PARP) at sites...
7.
Ndlovu H, Mokoala K, Lawal I, Emmett L, Sathekge M
PET Clin
. 2024 Apr;
19(3):371-388.
PMID: 38658230
Novel prostate-specific membrane antigen (PSMA) ligands labeled with α-emitting radionuclides are sparking a growing interest in prostate cancer treatment. These targeted alpha therapies (TATs) have attractive physical properties that deem...
8.
Lawal I, Abubakar S, Ndlovu H, Mokoala K, More S, Sathekge M
Mol Diagn Ther
. 2024 Mar;
28(3):265-289.
PMID: 38555542
Theranostics with radioligands (radiotheranostics) has played a pivotal role in oncology. Radiotheranostics explores the molecular targets expressed on tumor cells to target them for imaging and therapy. In this way,...
9.
Ndlovu H, Lawal I, Mokoala K, Sathekge M
Int J Mol Sci
. 2024 Feb;
25(3).
PMID: 38338854
Breast cancer is the most frequently diagnosed cancer and leading cause of cancer-related deaths worldwide. Timely decision-making that enables implementation of the most appropriate therapy or therapies is essential for...
10.
Koatale P, Welling M, Ndlovu H, Kgatle M, Mdanda S, Mdlophane A, et al.
ACS Infect Dis
. 2024 Jan;
10(2):270-286.
PMID: 38290525
The unique structural architecture of the peptidoglycan allows for the stratification of bacteria as either Gram-negative or Gram-positive, which makes bacterial cells distinguishable from mammalian cells. This classification has received...