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Mikael Bjornstedt

Explore the profile of Mikael Bjornstedt including associated specialties, affiliations and a list of published articles. Areas
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Articles 72
Citations 1550
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Recent Articles
1.
Razaghi A, Bjornstedt M
Cancers (Basel) . 2024 Jul; 16(13). PMID: 39001444
Selenoprotein P (SELENOP) acts as a crucial mediator, distributing selenium from the liver to other tissues within the body. Despite its established role in selenium metabolism, the specific functions of...
2.
Razaghi A, Durand-Dubief M, Brusselaers N, Bjornstedt M
Front Immunol . 2023 Sep; 14:1249330. PMID: 37691915
PD-1 and PD-L1 are crucial regulators of immunity expressed on the surface of T cells and tumour cells, respectively. Cancer cells frequently use PD-1/PD-L1 to evade immune detection; hence, blocking...
3.
He F, Tay A, Calandigary A, Malki E, Suzuki S, Liu T, et al.
Cancer Res . 2023 Mar; 83(10):1628-1645. PMID: 36919330
Significance: FPR2 is a sex-dependent mediator of macrophage function in pancreatic cancer and can be targeted to reprogram macrophages and stimulate antitumor immunity in females.
4.
Breuer O, Brodin O, Razaghi A, Brodin D, Gammelgaard B, Bjornstedt M
Biomedicines . 2023 Feb; 11(2). PMID: 36830832
Cancer is one of the main causes of human death globally and novel chemotherapeutics are desperately required. As a simple selenium oxide, selenite is a very promising chemotherapeutic because of...
5.
Kamp J, Kappe N, Moro C, Fuge J, Kuehnel M, Wrenger S, et al.
Int J Mol Sci . 2023 Feb; 24(3). PMID: 36768808
PiZZ (Glu342Lys) α1-antitrypsin deficiency (AATD) is characterized by intrahepatic AAT polymerization and is a risk factor for liver disease development in children. The majority of PiZZ children are disease free,...
6.
Szekerczes T, Selvam A, Moro C, Elduayen S, Dillner J, Bjornstedt M, et al.
Antioxidants (Basel) . 2023 Jan; 12(1). PMID: 36671030
Patient-derived tissue culture models are valuable tools to investigate drug effects and targeted treatment approaches. Resected tumor slices cultured ex vivo have recently gained interest in precision medicine, since they...
7.
Razaghi A, Szakos A, Alouda M, Bozoky B, Bjornstedt M, Szekely L
Diagnostics (Basel) . 2022 Nov; 12(11). PMID: 36428847
Critically ill COVID-19 patients with pleural effusion experience longer hospitalization, multisystem inflammatory syndrome, and higher rates of mortality. Generally, pleural effusion can serve as a diagnostic value to differentiate cytokine...
8.
Moro C, Selvam A, Ghaderi M, Pimenoff V, Gerling M, Bozoky B, et al.
Front Oncol . 2022 Sep; 12:965182. PMID: 36059619
Pancreatic ductal adenocarcinoma (PDAC) is the most common type of pancreatic cancer. PDAC has a dismal prognosis and an inherent resistance to cytostatic drugs. The lack of reliable experimental models...
9.
Razaghi A, Mansouri L, Brodin O, Bjornstedt M, Lundahl J
Front Oncol . 2022 Jun; 12:906134. PMID: 35720000
A high expression level of programmed death-ligand 1 (PD-L1) is observed in different types of cancers (particularly lung cancer). Soluble (s)PD-L1 may be used as a prognostic marker and a...
10.
Razaghi A, Szakos A, Al-Shakarji R, Bjornstedt M, Szekely L
Scand Cardiovasc J . 2022 Jun; 56(1):166-173. PMID: 35678649
Patients with underlying heart diseases have a higher risk of dying from Covid-19. It has also been suggested that Covid-19 affects the heart through myocarditis. Despite the rapidly growing research...