Mika Saarela
Overview
Explore the profile of Mika Saarela including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
78
Followers
0
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Recent Articles
1.
Sarkkinen J, Yohannes D, Kreivi N, Durnsteiner P, Elsakova A, Huuhtanen J, et al.
Sci Immunol
. 2025 Feb;
10(104):eadl3604.
PMID: 39982975
Multiple sclerosis (MS) is an autoimmune disease of the central nervous system, and Epstein-Barr virus (EBV) infection is a prerequisite for developing the disease. However, the pathogenic mechanisms that lead...
2.
Pitkanen H, Haapio M, Saarela M, Taskinen M, Brinkman H, Lassila R
Transfus Apher Sci
. 2024 Mar;
63(3):103918.
PMID: 38555232
Introduction: Therapeutic plasma exchange (TPE), with solvent/detergent (S/D)-treated plasma as replacement fluid, is an extracorporeal blood purification technique with major impact on both coagulation and lipids. Our previous in vitro...
3.
Honkimaa A, Laine P, Suppula J, Tynninen O, Saarela M, Laakso S, et al.
J Infect Dis
. 2024 Feb;
230(3):e732-e736.
PMID: 38365889
Progressive multifocal leukoencephalopathy (PML) is a rare neurological condition associated with reactivation of dormant JC polyomavirus (JCPyV). In this study, we characterized gene expression and JCPyV rearrangements in PML brain...
4.
Auvinen E, Honkimaa A, Laine P, Passerini S, Moens U, Pietropaolo V, et al.
J Clin Virol
. 2024 Feb;
171:105652.
PMID: 38364704
Background: JC polyomavirus (JCPyV) persists asymptomatic in more than half of the human population. Immunocompromising conditions may cause reactivation and acquisition of neurotropic rearrangements in the viral genome, especially in...
5.
Honkimaa A, Suppula J, Tynninen O, Saarela M, Liimatainen H, Laine P, et al.
J Infect Dis
. 2023 Mar;
228(7):829-833.
PMID: 36988117
Progressive multifocal leukoencephalopathy (PML) is a severe neurological condition caused by reactivation of JC polyomavirus (JCPyV) in immunosuppression. Asymptomatic JCPyV persists in peripheral tissues. Upon reactivation, neurotropic rearrangements may emerge,...
6.
Merkies I, van Schaik I, Leger J, Bril V, van Geloven N, Hartung H, et al.
J Peripher Nerv Syst
. 2019 Jan;
24(1):48-55.
PMID: 30672091
Intravenous immunoglobulin (IVIG) is a potential therapy for chronic inflammatory demyelinating polyneuropathy (CIDP). To investigate the efficacy and safety of the IVIG IgPro10 (Privigen) for treatment of CIDP, results from...
7.
Saarela M, Senthil K, Jones J, Tienari P, Soilu-Hanninen M, Airas L, et al.
Neurology
. 2018 Apr;
90(18):849-851.
PMID: 29602914
No abstract available.
8.
Atula S, Pfau K, Salmi T, Sihvo E, Haapio M, Saarela M, et al.
Duodecim
. 2017 Dec;
133(11):1053-62.
PMID: 29243896
Myasthenia gravis (MG) is the most common neuromuscular transmission disorder, causing weakness of skeletal muscles on exertion. The course of the disease is highly variable, symptoms and signs may change...
9.
Merkies I, Lawo J, Edelman J, De Bleecker J, Sommer C, Robberecht W, et al.
J Peripher Nerv Syst
. 2017 Jun;
22(2):149-152.
PMID: 28594116
No abstract available.
10.
Seppala H, Virtanen E, Saarela M, Laine P, Paulin L, Mannonen L, et al.
J Infect Dis
. 2017 Apr;
215(6):889-895.
PMID: 28453853
Background: Progressive multifocal leukoencephalopathy (PML) is a fatal disease caused by reactivation of JC polyomavirus (JCPyV) in immunosuppressed individuals and lytic infection by neurotropic JCPyV in glial cells. The exact...