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Miguel Oliveira Santos

Explore the profile of Miguel Oliveira Santos including associated specialties, affiliations and a list of published articles. Areas
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Articles 65
Citations 148
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Recent Articles
11.
Simao S, Oliveira Santos M, Gromicho M, Martins I, de Carvalho M
Amyotroph Lateral Scler Frontotemporal Degener . 2024 Aug; 25(7-8):726-736. PMID: 39101689
: Amyotrophic lateral sclerosis (ALS) has heterogeneous manifestations ranging from motor neuron degeneration to cognitive and behavioral impairment. This study aims to clarify the interactions between cognition and behavioral symptoms...
12.
Correia J, Gromicho M, Pronto-Laborinho A, Oliveira Santos M, de Carvalho M
Brain Sci . 2024 Jul; 14(7). PMID: 39061402
Respiratory dysfunction is an important hallmark of amyotrophic lateral sclerosis (ALS). Elevation of creatine kinase (CK) has been reported in 23-75% of ALS patients, but the underlying mechanisms remain unknown....
13.
Oliveira Santos M, de Carvalho M
Expert Rev Neurother . 2024 May; 24(6):549-553. PMID: 38758193
Introduction: Amyotrophic lateral sclerosis (ALS) is a rapidly progressive motor neuron disorder with a fatal outcome 3-5 years after disease onset due to respiratory complications. Superoxide dismutase 1 (SOD1) mutations...
14.
Santos Silva C, Correia Rodrigues C, Baptista M, Oliveira Santos M, Gromicho M, Carvalho V, et al.
Muscle Nerve . 2024 Apr; 70(1):152-156. PMID: 38687249
Introduction/aims: The frequency and distribution of upper motor neuron (UMN) signs in primary lateral sclerosis (PLS) are unknown. We aimed to study the spectrum of UMN signs in PLS and...
15.
Oliveira Santos M, Domingues S, Falcao de Campos C, Moreira S, de Carvalho M
J Neurol Sci . 2024 Apr; 460:123021. PMID: 38653115
Background: Late-onset Pompe disease (LOPD) patients may still need ventilation support at some point of their disease course, despite regular recombinant human alglucosidase alfa treatment. This suggest that other pathophysiological...
16.
Oliveira Santos M, Santos I, Sacramento G, Oliveira R, Castanheira A
Cureus . 2024 Apr; 16(3):e55978. PMID: 38618380
Dermatomyositis (DM) is an inflammatory myopathy often paraneoplastic in nature. Patients have characteristic cutaneous findings and possible muscle involvement. In the latter, muscle enzymes are elevated, and the electromyogram shows...
17.
Serrao C, Domingues S, Falcao de Campos C, Moreira S, Conceicao I, de Carvalho M, et al.
Neurol Sci . 2024 Apr; 45(6):2887-2891. PMID: 38589769
Introduction: Nusinersen was approved for 5q spinal muscular atrophy (SMA), irrespective of age, SMA type or functional status. Nonetheless, long-term data on adults with milder phenotypes are scarce. We aimed...
18.
Tortorella M, Alves I, Gromicho M, Oliveira Santos M, de Carvalho M
J Neurol Sci . 2024 Jan; 457:122895. PMID: 38267282
No abstract available.
19.
Castro J, Oliveira Santos M, Swash M, de Carvalho M
Muscle Nerve . 2024 Jan; 69(3):303-312. PMID: 38220221
Introduction/aims: In amyotrophic lateral sclerosis (ALS), the role of spinal interneurons in ALS is underrecognized. We aimed to investigate pre- and post-synaptic modulation of spinal motor neuron excitability by studying...
20.
Oliveira Santos M, Swash M, de Carvalho M
Expert Rev Neurother . 2023 Dec; 24(1):45-53. PMID: 38093670
Introduction: Primary lateral sclerosis (PLS) is a rare, adult-onset and slowly progressive motor neuron disorder whose clinical core is characterized by upper motor neuron (UMN) dysfunction. Its formal diagnosis is...