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Miguel L Concha

Explore the profile of Miguel L Concha including associated specialties, affiliations and a list of published articles. Areas
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Articles 55
Citations 1325
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Recent Articles
1.
Borgonovo J, Allende-Castro C, Medinas D, Cardenas D, Cuevas M, Hetz C, et al.
Cell Tissue Res . 2023 Nov; 395(1):21-38. PMID: 38015266
Nothobranchius furzeri is emerging as an exciting vertebrate organism in the field of biomedicine, developmental biology and ecotoxicology research. Its short generation time, compressed lifespan and accelerated ageing make it...
2.
Gatica M, Navarro C, Lavado A, Reig G, Pulgar E, Llanos P, et al.
BMC Bioinformatics . 2023 Jul; 24(1):283. PMID: 37438714
Motivation: Quantitative descriptions of multi-cellular structures from optical microscopy imaging are prime to understand the variety of three-dimensional (3D) shapes in living organisms. Experimental models of vertebrates, invertebrates and plants,...
3.
Montenegro-Rojas I, Yanez G, Skog E, Guerrero-Calvo O, Andaur-Lobos M, Dolfi L, et al.
Front Cell Dev Biol . 2023 Apr; 11:959611. PMID: 37020464
Deciphering the biological and physical requirements for the outset of multicellularity is limited to few experimental models. The early embryonic development of annual killifish represents an almost unique opportunity to...
4.
Figueroa D, Rios J, Araneda O, Contreras H, Concha M, Garcia C
Life (Basel) . 2023 Jan; 13(1). PMID: 36675964
Toxins of the OA-group (okadaic acid, OA; dinophysistoxin-1, DTX-1) are the most prevalent in the fjords of southern Chile, and are characterized by their potential harmful effects on aquatic organisms....
5.
Palma K, Signore I, Meynard M, Ibarra J, Armijo-Weingart L, Cayuleo M, et al.
Front Cell Dev Biol . 2022 Dec; 10:999265. PMID: 36568973
The parapineal organ is a midline-derived epithalamic structure that in zebrafish adopts a left-sided position at embryonic stages to promote the development of left-right asymmetries in the habenular nuclei. Despite...
6.
Michel L, Palma K, Cerda M, Lagadec R, Mayeur H, Fuentes M, et al.
Front Cell Dev Biol . 2022 Nov; 10:1015074. PMID: 36407110
Habenulae asymmetries are widespread across vertebrates and analyses in zebrafish, the reference model organism for this process, have provided insight into their molecular nature, their mechanisms of formation and their...
7.
Concha M, Reig G
Philos Trans R Soc Lond B Biol Sci . 2022 Oct; 377(1865):20210264. PMID: 36252221
Teleost eggs have evolved a highly derived early developmental pattern within vertebrates as a result of the meroblastic cleavage pattern, giving rise to a polar stratified architecture containing a large...
8.
Perez-Verdugo F, Reig G, Cerda M, Concha M, Soto R
J R Soc Interface . 2022 Jan; 19(186):20210851. PMID: 35078339
Several models have been proposed to describe the dynamics of epithelial tissues undergoing morphogenetic changes driven by apical constriction pulses, which differ in where the constriction is applied, either at...
9.
Medinas D, Malik S, Yildiz-Bolukbasi E, Borgonovo J, Saaranen M, Urra H, et al.
EMBO J . 2021 Dec; 41(2):e105531. PMID: 34904718
Recessive gene mutations underlie many developmental disorders and often lead to disabling neurological problems. Here, we report identification of a homozygous c.170G>A (p.Cys57Tyr or C57Y) mutation in the gene coding...
10.
Pihan P, Lisbona F, Borgonovo J, Edwards-Jorquera S, Nunes-Hasler P, Castillo K, et al.
Sci Adv . 2021 Nov; 7(46):eabe5469. PMID: 34767445
Programmed cell death is regulated by the balance between activating and inhibitory signals. Here, we have identified RECS1 (responsive to centrifugal force and shear stress 1) [also known as TMBIM1...