Miguel Gijon
Overview
Explore the profile of Miguel Gijon including associated specialties, affiliations and a list of published articles.
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5
Citations
1592
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Recent Articles
1.
Elaimy A, El-Derany M, James J, Wang Z, Pearson A, Holcomb E, et al.
JCI Insight
. 2024 Sep;
9(21).
PMID: 39287988
End-stage liver disease is marked by portal hypertension, systemic elevations in ammonia, and development of hepatocellular carcinoma (HCC). While these clinical consequences of cirrhosis are well described, it remains poorly...
2.
Liao P, Wang W, Wang W, Kryczek I, Li X, Bian Y, et al.
Cancer Cell
. 2022 Feb;
40(4):365-378.e6.
PMID: 35216678
Tumor cell intrinsic ferroptosis-initiating mechanisms are unknown. Here, we discover that T cell-derived interferon (IFN)γ in combination with arachidonic acid (AA) induces immunogenic tumor ferroptosis, serving as a mode of...
3.
Wang W, Green M, Choi J, Gijon M, Kennedy P, Johnson J, et al.
Nature
. 2019 May;
569(7755):270-274.
PMID: 31043744
Cancer immunotherapy restores or enhances the effector function of CD8 T cells in the tumour microenvironment. CD8 T cells activated by cancer immunotherapy clear tumours mainly by inducing cell death...
4.
Poczobutt J, Nguyen T, Hanson D, Li H, Sippel T, Weiser-Evans M, et al.
J Immunol
. 2015 Dec;
196(2):891-901.
PMID: 26663781
Eicosanoids, including PGs, produced by cyclooxygenases (COX), and leukotrienes, produced by 5-lipoxygenase (5-LO) have been implicated in cancer progression. These molecules are produced by both cancer cells and the tumor...
5.
Poczobutt J, Gijon M, Amin J, Hanson D, Li H, Walker D, et al.
PLoS One
. 2013 Nov;
8(11):e79633.
PMID: 24244531
Eicosanoids are bioactive lipid mediators derived from arachidonic acid(1) (AA), which is released by cytosolic phospholipase A2 (cPLA2). AA is metabolized through three major pathways, cyclooxygenase (COX), lipoxygenase (LO) and...