Mieke Geens
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Explore the profile of Mieke Geens including associated specialties, affiliations and a list of published articles.
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25
Citations
521
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Recent Articles
11.
Nguyen H, Markouli C, Geens M, Barbe L, Sermon K, Spits C
Mol Hum Reprod
. 2014 Aug;
20(10):981-9.
PMID: 25082980
It is well known that human embryonic stem cells (hESCs) frequently acquire recurrent chromosomal abnormalities, very reminiscent of those found in cancerous cells. Given the parallels between cancer and stem...
12.
Jacobs K, Mertzanidou A, Geens M, Nguyen H, Staessen C, Spits C
Nat Commun
. 2014 Jun;
5:4227.
PMID: 24970340
Current knowledge on chromosomal mosaicism in human cell cultures is mostly based on cytogenetic banding methods. The recent development of high-resolution full-genome analysis methods applicable to single cells is providing...
13.
Sui L, Geens M, Sermon K, Bouwens L, Mfopou J
Stem Cell Rev Rep
. 2013 Mar;
9(5):569-77.
PMID: 23468018
Transplantation of pancreatic progenitors derived from human embryonic stem cells (hESCs) is a promising way to treat diabetes. Strategies to obtain the required cell mass would rely on the up...
14.
Van Haute L, Spits C, Geens M, Seneca S, Sermon K
Nat Biotechnol
. 2013 Jan;
31(1):20-3.
PMID: 23302926
No abstract available.
15.
Sui L, Mfopou J, Geens M, Sermon K, Bouwens L
Biochem Biophys Res Commun
. 2012 Sep;
426(3):380-5.
PMID: 22960178
Considering their unlimited proliferation and pluripotency properties, human embryonic stem cells (hESCs) constitute a promising resource applicable for cell replacement therapy. To facilitate this clinical translation, it is critical to...
16.
Mateizel I, Geens M, Van de Velde H, Sermon K
Methods Mol Biol
. 2012 Apr;
873:81-112.
PMID: 22528350
More than 600 human embryonic stem cell (hESC) lines have been reported today at the human European Embryonic Stem Cell Registry ( http://www.hescreg.eu/ ). Despite these high numbers, there are...
17.
Geens M, Sermon K, Van de Velde H, Tournaye H
J Assist Reprod Genet
. 2011 Feb;
28(5):471-80.
PMID: 21318592
Purpose: To investigate the spontaneous germ cell differentiation capacity of VUB hESC lines, develop a protocol for the induction of germ cell differentiation using conditioned medium from Sertoli cells (SCCM)...
18.
Geens M, Goossens E, Tournaye H
Fertil Steril
. 2010 Nov;
95(2):787-91.
PMID: 21055744
Objective: To investigate whether a selective matrix adhesion-based protocol can enrich germ cells and deplete cancer cells from contaminated human testicular cell suspensions. Design: Artificially contaminated and control testicular cell...
19.
Ning L, Goossens E, Geens M, Van Saen D, Van Riet I, He D, et al.
Hum Reprod
. 2010 Oct;
25(12):3101-9.
PMID: 20940138
Background: The aim of this study was to explore the plasticity and transdifferentiation potential of murine spermatogonial stem cells (SSCs) into hematopoietic cells. Methods: GFP(+)CD49f(+)H-2K(b-) SSCs of male donor mice...
20.
Geens M, Mateizel I, Sermon K, De Rycke M, Spits C, Cauffman G, et al.
Hum Reprod
. 2009 Jul;
24(11):2709-17.
PMID: 19633307
Background: Recently, we demonstrated that single blastomeres of a 4-cell stage human embryo are able to develop into blastocysts with inner cell mass and trophectoderm. To further investigate potency at...