Mieke C Louwe
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Explore the profile of Mieke C Louwe including associated specialties, affiliations and a list of published articles.
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16
Citations
244
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Recent Articles
11.
Sokolova M, Ranheim T, Louwe M, Halvorsen B, Yndestad A, Aukrust P
J Cardiovasc Pharmacol
. 2019 Oct;
74(4):276-284.
PMID: 31584530
Metabolic and immune systems are among the most fundamental requirements for survival. Many metabolic and immune response pathways or nutrient- and pathogen-sensing systems are evolutionarily conserved throughout species. As a...
12.
Shahini N, Ueland T, Auensen A, Michelsen A, Ludviksen J, Hussain A, et al.
J Immunol
. 2019 Sep;
203(7):1973-1980.
PMID: 31492744
Inflammation is involved in initiation and progression of aortic stenosis (AS). However, the role of the complement system, a crucial component of innate immunity in AS, is unclear. We hypothesized...
13.
Sokolova M, Sjaastad I, Louwe M, Alfsnes K, Aronsen J, Zhang L, et al.
Front Immunol
. 2019 Aug;
10:1621.
PMID: 31379826
Obesity is an increasingly prevalent metabolic disorder in the modern world and is associated with structural and functional changes in the heart. The NLRP3 inflammasome is an innate immune sensor...
14.
Shahini N, Michelsen A, Nilsson P, Ekholt K, Gullestad L, Broch K, et al.
Sci Rep
. 2017 Feb;
7:42532.
PMID: 28195242
The complement system, an important arm of the innate immune system, is activated in heart failure (HF). We hypothesized that HF patients are characterized by an imbalance of alternative amplification...
15.
Louwe M, Lammers B, Frias M, Foks A, de Leeuw L, Hildebrand R, et al.
Atherosclerosis
. 2016 Jun;
251:159-163.
PMID: 27323229
Background And Aims: We explored the role of ATP-binding cassette transporter A1 (Abca1), in post-myocardial infarction (MI) cardiac injury. Methods: In Abca1(-/-) mice, wild type (WT) mice, and WT mice...
16.
Kuhnast S, Louwe M, Heemskerk M, Pieterman E, van Klinken J, van den Berg S, et al.
PLoS One
. 2013 Jul;
8(6):e66467.
PMID: 23840481
Objective: Niacin potently lowers triglycerides, mildly decreases LDL-cholesterol, and largely increases HDL-cholesterol. Despite evidence for an atheroprotective effect of niacin from previous small clinical studies, the large outcome trials, AIM-HIGH...
17.
Louwe M, van der Hoorn J, van den Berg S, Jukema J, Romijn J, Willems van Dijk K, et al.
Appl Physiol Nutr Metab
. 2012 Mar;
37(2):214-24.
PMID: 22380727
Increased availability of fatty acids released from insulin-resistant adipose tissue may lead to excess fatty acid uptake in nonadipose organs, including the heart. Accumulation of toxic fatty acid intermediates may...
18.
Revsin Y, Rekers N, Louwe M, Saravia F, De Nicola A, de Kloet E, et al.
Neuropsychopharmacology
. 2008 Sep;
34(3):747-58.
PMID: 18784648
Type 1 diabetes is a common metabolic disorder accompanied by an increased secretion of glucocorticoids and cognitive deficits. Chronic excess of glucocorticoids per se can evoke similar neuropathological signals linked...