Mickey V Patel
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Explore the profile of Mickey V Patel including associated specialties, affiliations and a list of published articles.
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24
Citations
720
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Recent Articles
1.
Patel M, Shen Z, Wira C
Explor Immunol
. 2025 Feb;
2(5):677-692.
PMID: 39931230
Menopause signals the end of the reproductive period in women. However, fertility and fecundity decrease with increasing age prior to menopause demonstrating that changes in the premenopausal female reproductive tract...
2.
Vom Steeg L, Shen Z, Collins J, Patel M, Barr F, Hopkins D, et al.
Front Immunol
. 2025 Jan;
15:1506653.
PMID: 39872519
Epidemiological evidence suggests that post-menopausal women are more susceptible to HIV infection following sexual intercourse than are younger cohorts for reasons that remain unclear. Here, we evaluated how menopause-associated changes...
3.
Patel M, Shen Z, Hopkins D, Barr F, Wira C
Am J Reprod Immunol
. 2025 Jan;
93(1):e70031.
PMID: 39777771
Problem: Aging alters immune function in women and can lead increased risk of infections, particularly in the female reproductive tract (FRT). Method Of Study: To determine how aging affects innate...
4.
Shen Z, Vom Steeg L, Patel M, Rodriguez-Garcia M, Wira C
Front Immunol
. 2024 Sep;
15:1465124.
PMID: 39328419
Since CD4+ T cells are essential for regulating adaptive immune responses and for long lasting mucosal protection, changes in CD4+ T cell numbers and function are likely to affect protective...
5.
Shen Z, Patel M, Rodriguez-Garcia M, Wira C
Immun Ageing
. 2022 Nov;
19(1):55.
PMID: 36371240
Background: Regulation of endometrial (EM) CD8+ T cells, which provide protection through cell-mediated cytotoxicity, is essential for successful reproduction, and protection against sexually transmitted infections and potential tumors. We have...
6.
Hughes S, Levy C, Katz R, Lokken E, Anahtar M, Hall M, et al.
BMC Med
. 2022 Oct;
20(1):353.
PMID: 36195867
Background: Hormonal changes during the menstrual cycle play a key role in shaping immunity in the cervicovaginal tract. Cervicovaginal fluid contains cytokines, chemokines, immunoglobulins, and other immune mediators. Many studies...
7.
Patel M, Rodriguez-Garcia M, Shen Z, Wira C
Sci Rep
. 2021 Dec;
11(1):23246.
PMID: 34853394
Mucosal integrity in the endometrium is essential for immune protection. Since breaches or injury to the epithelial barrier exposes underlying tissue and is hypothesized to increase infection risk, we determined...
8.
Patel M, Hopkins D, Barr F, Wira C
Front Immunol
. 2021 Oct;
12:718380.
PMID: 34630393
Estradiol (E) and progesterone (P) have potent effects on immune function in the human uterine endometrium which is essential for creating an environment conducive for successful reproduction. Type III/lambda (λ)...
9.
Patel M, Shen Z, Rodriguez-Garcia M, Usherwood E, Tafe L, Wira C
Front Immunol
. 2021 May;
12:657326.
PMID: 33968059
Endometrial cancer is the most common gynecological cancer. To investigate how it suppresses host immune function, we isolated CD8+ T cells from endometrial endometroid carcinomas and adjacent non-cancerous endometrium and...
10.
Rodriguez-Garcia M, Patel M, Shen Z, Wira C
Aging Cell
. 2021 May;
20(5):e13361.
PMID: 33951269
Mucosal tissues in the human female reproductive tract (FRT) are primary sites for both gynecological cancers and infections by a spectrum of sexually transmitted pathogens, including human immunodeficiency virus (HIV),...