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Mickael Garnier

Explore the profile of Mickael Garnier including associated specialties, affiliations and a list of published articles. Areas
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Citations 104
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Recent Articles
1.
Girard F, Even A, Thierry A, Ruault M, Meneu L, Larrous P, et al.
EMBO J . 2025 Feb; PMID: 40016420
Natural plasmids are common in prokaryotes, but few have been documented in eukaryotes. The natural 2µ plasmid present in the yeast Saccharomyces cerevisiae is one of these best-characterized exceptions. This...
2.
Scelfo A, Angrisani A, Grillo M, Barnes B, Muyas F, Sauer C, et al.
Mol Cell . 2024 Feb; 84(6):1003-1020.e10. PMID: 38359824
The high incidence of whole-arm chromosome aneuploidy and translocations in tumors suggests instability of centromeres, unique loci built on repetitive sequences and essential for chromosome separation. The causes behind this...
3.
Loiodice I, Garnier M, Nikolov I, Taddei A
Cells . 2021 Nov; 10(11). PMID: 34831033
In eukaryotic cells, silent chromatin is mainly found at the nuclear periphery forming subnuclear compartments that favor silencing establishment. Here, we set up an inducible system to monitor silencing establishment...
4.
Torne J, Ray-Gallet D, Boyarchuk E, Garnier M, Le Baccon P, Coulon A, et al.
Nat Struct Mol Biol . 2020 Sep; 27(11):1057-1068. PMID: 32895554
Nucleosomes represent a challenge in regard to transcription. Histone eviction enables RNA polymerase II (RNAPII) progression through DNA, but compromises chromatin integrity. Here, we used the SNAP-tag system to distinguish...
5.
Hocher A, Ruault M, Kaferle P, Descrimes M, Garnier M, Morillon A, et al.
Genome Res . 2018 Oct; 28(12):1867-1881. PMID: 30355601
The eukaryotic genome is divided into chromosomal domains of heterochromatin and euchromatin. Transcriptionally silent heterochromatin is found at subtelomeric regions, leading to the telomeric position effect (TPE) in yeast, fly,...
6.
Clement C, Orsi G, Gatto A, Boyarchuk E, Forest A, Hajj B, et al.
Nat Commun . 2018 Aug; 9(1):3181. PMID: 30093638
DNA replication is a challenge for the faithful transmission of parental information to daughter cells, as both DNA and chromatin organization must be duplicated. Replication stress further complicates the safeguard...