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Michio Hara

Explore the profile of Michio Hara including associated specialties, affiliations and a list of published articles. Areas
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Articles 15
Citations 226
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Recent Articles
1.
Yamamoto A, Furuya S, Takiguchi K, Hirayama K, Hara M, Sudo M, et al.
Gan To Kagaku Ryoho . 2021 Jan; 47(13):2071-2073. PMID: 33468804
50's man who have performed anterior pelvic exenteration with lateral lymph node dissection for rectal cancer with pT4bN0M0, pStage Ⅱc about 2 years ago, was admitted to our hospital for...
2.
Akazawa Y, Kono H, Hara M, Furuya S, Nakata Y, Wakana H, et al.
Anticancer Res . 2019 Sep; 39(9):4787-4794. PMID: 31519580
Background/aim: The aim of this study was to investigate the effects of the macrophage colony-stimulating factor (M-CSF) receptor antagonist on hepatic carcinogenesis in mice. Materials And Methods: Mice were injected...
3.
Kono H, Fujii H, Furuya S, Hara M, Hirayama K, Akazawa Y, et al.
World J Gastroenterol . 2016 Nov; 22(39):8779-8789. PMID: 27818593
Aim: To investigate the role of macrophage colony-stimulating factor (M-CSF) in patients with hepatocellular carcinoma (HCC) after surgery. Methods: Expression of M-CSF, distribution of M2 macrophages (MΦs), and angiogenesis were...
4.
Sun C, Kono H, Furuya S, Hara M, Hirayama K, Akazawa Y, et al.
Dig Dis Sci . 2015 Oct; 61(2):474-88. PMID: 26467699
Aim: The aim of the present study was to investigate the role of interleukin (IL)-17A in the initiation and progression of hepatocellular carcinoma. Methods: IL-17A deficient (KO) and wild-type (WT)...
5.
Furuya S, Kono H, Hara M, Hirayama K, Sun C, Fujii H
J Surg Res . 2015 Jul; 199(2):487-93. PMID: 26141869
Background: Lipopolysaccharide/d-galactosamine (LPS/GalN)-induced hepatic injury is an experimental model of fulminant hepatic failure in which tumor necrosis factor alpha (TNF-α) plays a pivotal role. Moreover, it was reported from our...
6.
Yoshimura K, Mandal M, Hara M, Fujii H, Chen L, Tanabe K, et al.
Anal Biochem . 2013 Jul; 441(1):32-7. PMID: 23851340
Real-time analyses of hepatocellular carcinoma were performed in living mice to assess the applicability of probe electrospray ionization-mass spectrometry (PESI-MS) in medical diagnosis. The number of peaks and the abundance...
7.
Hara M, Kono H, Furuya S, Hirayama K, Tsuchiya M, Fujii H
Hepatol Res . 2013 May; 44(7):798-811. PMID: 23710613
Aim: The specific purpose of this study was to investigate the role of macrophage colony-stimulating factor (M-CSF) in initiation and progression of hepatocellular carcinoma using M-CSF-deficient mice. Methods: M-CSF-deficient (osteopetrotic:...
8.
Furuya S, Kono H, Hara M, Hirayama K, Tsuchiya M, Fujii H
J Surg Res . 2013 Apr; 184(2):838-46. PMID: 23590864
Background: Liver regeneration after partial hepatectomy (PH) is regulated by tumor necrosis factor (TNF)-α derived from the Kupffer cell. Furthermore, it was reported from our laboratory that interleukin (IL)-17A enhances...
9.
Hara M, Kono H, Furuya S, Hirayama K, Tsuchiya M, Fujii H
J Surg Res . 2013 Apr; 183(2):574-82. PMID: 23578751
Background: It was recently reported that serum interleukin (IL)-17 levels increased in liver fibrosis associated with human alcoholic liver disease. However, the role of IL-17 in liver fibrosis has not...
10.
Kono H, Fujii H, Ogiku M, Hosomura N, Amemiya H, Tsuchiya M, et al.
J Immunol . 2011 Sep; 187(9):4818-25. PMID: 21949019
Recent evidence suggests that IL-17A regulates neutrophil-dependent organ injury. Accordingly, the purpose of this study was to determine the role of IL-17A in neutrophil recruitment after ischemia-reperfusion (I/R) and in...