Michiel Kleerebezem
Overview
Explore the profile of Michiel Kleerebezem including associated specialties, affiliations and a list of published articles.
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259
Citations
16194
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Recent Articles
1.
van Olst B, Boeren S, Vervoort J, Kleerebezem M
mBio
. 2025 Feb;
16(3):e0299024.
PMID: 39976430
Fitness optimization in a dynamic environment requires bacteria to adapt their proteome in a tightly regulated manner by altering protein production and/or degradation. Here, we investigate proteome adaptation in following...
2.
Kleerebezem M, Fuhren J
Microbiome Res Rep
. 2025 Jan;
3(4):46.
PMID: 39741951
Synbiotics are defined as "a mixture comprising live microorganisms and substrate(s) selectively utilized by host microorganisms that confers a health benefit on the host". The definition discriminates between synergistic and...
3.
van der Els S, Boekhorst J, Bron P, Kleerebezem M
BMC Genomics
. 2024 Jul;
25(1):734.
PMID: 39080539
Dairy industries apply selected lactococcal strains and mixed cultures to produce diverse fermented products with distinctive flavor and texture properties. Innovation of the starter culture functionality in cheese applications embraces...
4.
Fuhren J, Schwalbe M, Boekhorst J, Rosch C, Schols H, Kleerebezem M
Gut Microbes
. 2024 Apr;
16(1):2338946.
PMID: 38656273
Synbiotics combine the concepts of probiotics and prebiotics to synergistically enhance the health-associated effects of both components. Previously, we have shown that the intestinal persistence of inulin-utilizing Lp900 is significantly...
5.
van Olst B, Nugroho A, Boeren S, Vervoort J, Bachmann H, Kleerebezem M
Food Microbiol
. 2024 Apr;
121:104514.
PMID: 38637076
The enzymatic repertoire of starter cultures belonging to the Lactococcus genus determines various important characteristics of fermented dairy products but might change in response to the substantial environmental changes in...
6.
van der Els S, Sheombarsing R, van Kempen T, Wels M, Boekhorst J, Bron P, et al.
BMC Genomics
. 2024 Apr;
25(1):324.
PMID: 38561675
Lactococcus lactis is widely applied by the dairy industry for the fermentation of milk into products such as cheese. Adaptation of L. lactis to the dairy environment often depends on...
7.
Douwenga S, van Olst B, Boeren S, Luo Y, Lai X, Teusink B, et al.
Microbiol Spectr
. 2023 Oct;
11(6):e0224823.
PMID: 37888986
The availability of nutrients to microorganisms varies considerably between different environments, and changes can occur rapidly. As a general rule, a fast growth rate-typically growth on glucose-is associated with the...
8.
Zaccaria E, Klaassen T, Alleleyn A, Boekhorst J, Chervaux C, Smokvina T, et al.
Gut Microbes
. 2023 Aug;
15(1):2244720.
PMID: 37589280
Fermented foods and beverages are a significant source of dietary bacteria that enter the gastrointestinal (GI) tract. However, little is known about how these microbes survive and adapt to the...
9.
Prochazkova N, Venlet N, Hansen M, Lieberoth C, Dragsted L, Bahl M, et al.
Front Nutr
. 2023 Jun;
10:1187165.
PMID: 37324737
Background: Diets rich in whole grains are associated with health benefits. Yet, it remains unclear whether the benefits are mediated by changes in gut function and fermentation. Objective: We explored...
10.
Choudhury R, Gu Y, Bolhuis J, Kleerebezem M
Front Immunol
. 2023 Jun;
14:1208891.
PMID: 37304274
Introduction: Diet-microbiota-host interactions are increasingly studied to comprehend their implications in host metabolism and overall health. Keeping in mind the importance of early life programming in shaping intestinal mucosal development,...