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Michelle Zanette

Explore the profile of Michelle Zanette including associated specialties, affiliations and a list of published articles. Areas
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Articles 11
Citations 308
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Recent Articles
1.
Maese L, Loh M, Choi M, Lin T, Aoki E, Zanette M, et al.
Blood . 2022 Sep; 141(7):704-712. PMID: 36108304
AALL1931, a phase 2/3 study conducted in collaboration with the Children's Oncology Group, investigated the efficacy and safety of JZP458 (asparaginase erwinia chrysanthemi [recombinant]-rywn), a recombinant Erwinia asparaginase derived from...
2.
Farrar G, Molinuevo J, Zanette M
Eur J Nucl Med Mol Imaging . 2019 Mar; 46(6):1299-1308. PMID: 30863934
Purpose: Visual interpretation of PET [F]flutemetamol images relies on systematic review of five brain regions and is considered positive when an elevated signal is observed in at least one region....
3.
Westwood S, Baird A, Hye A, Ashton N, Nevado-Holgado A, Anand S, et al.
Front Aging Neurosci . 2019 Jan; 10:409. PMID: 30618716
Blood biomarkers may aid in recruitment to clinical trials of Alzheimer's disease (AD) modifying therapeutics by triaging potential trials participants for amyloid positron emission tomography (PET) or cerebrospinal fluid (CSF)...
4.
Thal D, Beach T, Zanette M, Lilja J, Heurling K, Chakrabarty A, et al.
Acta Neuropathol . 2018 Aug; 136(4):557-567. PMID: 30123935
The deposition of the amyloid β-protein (Aβ) in senile plaques is one of the histopathological hallmarks of Alzheimer's disease (AD). Aβ-plaques arise first in neocortical areas and, then, expand into...
5.
Wolk D, Sadowsky C, Safirstein B, Rinne J, Duara R, Perry R, et al.
JAMA Neurol . 2018 May; 75(9):1114-1123. PMID: 29799984
Importance: Patients with amnestic mild cognitive impairment (aMCI) may progress to clinical Alzheimer disease (AD), remain stable, or revert to normal. Earlier progression to AD among patients who were β-amyloid...
6.
Owenius R, Zanette M, Cella P
J Nucl Med Technol . 2017 Oct; 45(4):297-303. PMID: 29042467
A heart-to-mediastinum (H/M) ratio of 1.6 or greater on planar I-iobenguane (I-MIBG) images identifies heart failure patients at low risk of experiencing an adverse cardiac event. This phase-4 study used...
7.
Salloway S, Gamez J, Singh U, Sadowsky C, Villena T, Sabbagh M, et al.
Alzheimers Dement (Amst) . 2017 Aug; 9:25-34. PMID: 28795133
Introduction: Performance of the amyloid tracer [F]flutemetamol was evaluated against three pathology standard of truth (SoT) measures including neuritic plaques (CERAD "original" and "modified" and the amyloid component of the...
8.
Miki T, Shimada H, Kim J, Yamamoto Y, Sugino M, Kowa H, et al.
Ann Nucl Med . 2017 Feb; 31(3):260-272. PMID: 28181118
Objective: This Phase 2 study assessed the performance of positron emission tomography (PET) brain images made with Flutemetamol F 18 Injection in detecting β-amyloid neuritic plaques in Japanese subjects. Methods:...
9.
Ikonomovic M, Buckley C, Heurling K, Sherwin P, Jones P, Zanette M, et al.
Acta Neuropathol Commun . 2016 Dec; 4(1):130. PMID: 27955679
In vivo imaging of fibrillar β-amyloid deposits may assist clinical diagnosis of Alzheimer's disease (AD), aid treatment selection for patients, assist clinical trials of therapeutic drugs through subject selection, and...
10.
Beach T, Thal D, Zanette M, Smith A, Buckley C
J Alzheimers Dis . 2016 Apr; 52(3):863-73. PMID: 27031469
Amyloid imaging is limited by an inconsistent relationship between cerebral cortex amyloid- β (Aβ) plaques and dementia. Autopsy studies suggest that Aβ plaques first appear in the cerebral cortex while...