Michelle M Jacobs
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Explore the profile of Michelle M Jacobs including associated specialties, affiliations and a list of published articles.
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13
Citations
441
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Recent Articles
1.
Wilson A, Jacobs M, Lambert T, Valada A, Meloni G, Gilmore E, et al.
bioRxiv
. 2025 Feb;
PMID: 39974894
For people with HIV (PWH), substance use disorders (SUDs) are a prominent neurological risk factor, and the impacts of both on dopaminergic pathways are a potential point of deleterious convergence....
2.
Ament S, Campbell R, Lobo M, Receveur J, Agrawal K, Borjabad A, et al.
Mol Psychiatry
. 2024 Jun;
29(12):3950-3961.
PMID: 38879719
Substance use disorders (SUD) and drug addiction are major threats to public health, impacting not only the millions of individuals struggling with SUD, but also surrounding families and communities. One...
3.
Morgello S, Cortes E, Gensler G, Meloni G, Jacobs M, Murray J, et al.
AIDS
. 2021 Apr;
35(9):1403-1412.
PMID: 33813555
Objective: Abnormal deposition of the antimicrobial peptide amyloid beta (Aβ) is a characteristic of Alzheimer's disease. The objective of this study was to elucidate risk factors for brain Aβ in...
4.
Egervari G, Jutras-Aswad D, Landry J, Miller M, Anderson S, Michaelides M, et al.
Neuropsychopharmacology
. 2016 Apr;
41(10):2512-20.
PMID: 27074815
Genetic factors impact behavioral traits relevant to numerous psychiatric disorders and risk-taking behaviors, and different lines of evidence have indicated that discrete neurobiological systems contribute to such individual differences. In...
5.
Trampush J, Jacobs M, Hurd Y, Newcorn J, Halperin J
Dev Sci
. 2014 Jan;
17(4):584-95.
PMID: 24410775
We tested the hypothesis that dopamine D1 and D2 receptor gene (DRD1 and DRD2, respectively) polymorphisms and the development of working memory skills can interact to influence symptom change over...
6.
Jacobs M, Murray J, Byrd D, Hurd Y, Morgello S
J Neurovirol
. 2013 Oct;
19(5):495-504.
PMID: 24078558
It has been postulated that drugs of abuse act synergistically with HIV, leading to increased neurotoxicity and neurocognitive impairment. The CNS impacts of HIV and drug use converge on the...
7.
Daws S, Whittard J, Jacobs M, Ren Y, Mazloom A, Caputi F, et al.
Biol Psychiatry
. 2013 May;
74(7):511-9.
PMID: 23702428
Background: Abuse of heroin and prescription opiate medications has grown to disturbing levels. Opioids mediate their effects through mu opioid receptors (MOR), but minimal information exists regarding MOR-related striatal signaling...
8.
Jutras-Aswad D, Jacobs M, Yiannoulos G, Roussos P, Bitsios P, Nomura Y, et al.
PLoS One
. 2012 Jun;
7(6):e39243.
PMID: 22745721
Background: Many young people experiment with cannabis, yet only a subgroup progress to dependence suggesting individual differences that could relate to factors such as genetics and behavioral traits. Dopamine receptor...
9.
Tomasiewicz H, Jacobs M, Wilkinson M, Wilson S, Nestler E, Hurd Y
Biol Psychiatry
. 2012 Jun;
72(10):803-10.
PMID: 22683090
Background: Marijuana use by teenagers often predates the use of harder drugs, but the neurobiological underpinnings of such vulnerability are unknown. Animal studies suggest enhanced heroin self-administration (SA) and dysregulation...
10.
Mice with altered serotonin 2C receptor RNA editing display characteristics of Prader-Willi syndrome
Morabito M, Abbas A, Hood J, Kesterson R, Jacobs M, Kump D, et al.
Neurobiol Dis
. 2010 Apr;
39(2):169-80.
PMID: 20394819
RNA transcripts encoding the 2C-subtype of serotonin (5HT(2C)) receptor undergo up to five adenosine-to-inosine editing events to encode twenty-four protein isoforms. To examine the effects of altered 5HT(2C) editing in...