Michelle Letarte
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Explore the profile of Michelle Letarte including associated specialties, affiliations and a list of published articles.
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49
Citations
1862
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Recent Articles
1.
Bernabeu C, Bayrak-Toydemir P, McDonald J, Letarte M
J Clin Med
. 2020 Nov;
9(11).
PMID: 33167572
Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant genetic disorder that presents with telangiectases in skin and mucosae, and arteriovenous malformations (AVMs) in internal organs such as lungs, liver, and...
2.
Kabelitz D, Letarte M, Gray C
Front Immunol
. 2019 Sep;
10:2012.
PMID: 31555265
One of the mandates of the International Union of Immunological Societies (IUIS) is to promote immunological education to young scientists across the globe, including a large focus on those from...
3.
Ermini L, Ausman J, Melland-Smith M, Yeganeh B, Rolfo A, Litvack M, et al.
Sci Rep
. 2017 Sep;
7(1):12172.
PMID: 28939895
Preeclampsia (PE), an hypertensive disorder of pregnancy, exhibits increased circulating levels of a short form of the auxillary TGF-beta (TGFB) receptor endoglin (sENG). Until now, its release and functionality in...
4.
Saito T, Bokhove M, Croci R, Zamora-Caballero S, Han L, Letarte M, et al.
Cell Rep
. 2017 Jun;
19(9):1917-1928.
PMID: 28564608
Endoglin (ENG)/CD105 is an essential endothelial cell co-receptor of the transforming growth factor β (TGF-β) superfamily, mutated in hereditary hemorrhagic telangiectasia type 1 (HHT1) and involved in tumor angiogenesis and...
5.
Jerkic M, Letarte M
FASEB J
. 2015 May;
29(9):3678-88.
PMID: 25972355
Endoglin (ENG) is a TGF-β superfamily coreceptor essential for vascular endothelium integrity. ENG mutations lead to a vascular dysplasia associated with frequent hemorrhages in multiple organs, whereas ENG null mouse...
6.
Contribution of oxidative stress to endothelial dysfunction in hereditary hemorrhagic telangiectasia
Jerkic M, Letarte M
Front Genet
. 2015 Mar;
6:34.
PMID: 25763011
Oxidative stress causes endothelial dysfunction and is implicated in the pathogenesis of cardiovascular diseases. Our studies suggested that reactive oxygen species (ROS) play a crucial role in hereditary hemorrhagic telangiectasia...
7.
Ardelean D, Letarte M
Front Genet
. 2015 Feb;
6:35.
PMID: 25717337
Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant vascular dysplastic disorder, characterized by recurrent nosebleeds (epistaxis), multiple telangiectases and arteriovenous malformations (AVMs) in major organs. Mutations in Endoglin (ENG or...
8.
Cheng K, Mariampillai A, Lee K, Vuong B, Luk T, Ramjist J, et al.
J Biomed Opt
. 2014 Aug;
19(8):086015.
PMID: 25140883
Speckle statistics of flowing scatterers have been well documented in the literature. Speckle variance optical coherence tomography exploits the large variance values of intensity changes in time caused mainly by...
9.
Peter M, Jerkic M, Sotov V, Douda D, Ardelean D, Ghamami N, et al.
Mediators Inflamm
. 2014 Aug;
2014:767185.
PMID: 25114380
Endoglin is a coreceptor of the TGF-β superfamily predominantly expressed on the vascular endothelium and selective subsets of immune cells. We previously demonstrated that Endoglin heterozygous (Eng (+/-)) mice subjected...
10.
Kapur N, Qiao X, Paruchuri V, Mackey E, Daly G, Ughreja K, et al.
J Am Heart Assoc
. 2014 Jul;
3(4).
PMID: 25015075
Background: Right ventricular (RV) failure is a major cause of mortality worldwide and is often a consequence of RV pressure overload (RVPO). Endoglin is a coreceptor for the profibrogenic cytokine,...