Michelle A Loprieno
Overview
Explore the profile of Michelle A Loprieno including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
14
Citations
305
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Walter M, Haick A, Riley R, Massa P, Strongin D, Klouser L, et al.
Nat Commun
. 2024 Sep;
15(1):8161.
PMID: 39289368
Gene drives are genetic modifications designed to propagate efficiently through a population. Most applications rely on homologous recombination during sexual reproduction in diploid organisms such as insects, but we recently...
2.
Aubert M, Haick A, Strongin D, Klouser L, Loprieno M, Stensland L, et al.
Nat Commun
. 2024 May;
15(1):4018.
PMID: 38740820
Anti-HSV therapies are only suppressive because they do not eliminate latent HSV present in ganglionic neurons, the source of recurrent disease. We have developed a potentially curative approach against HSV...
3.
Colon-Thillet R, Stone D, Loprieno M, Klouser L, Roychoudhury P, Santo T, et al.
Microbiol Spectr
. 2023 May;
11(3):e0517622.
PMID: 37199630
Hepatitis B virus (HBV) is a pathogen of major public health importance that is largely incurable once a chronic infection is established. Only humans and great apes are fully permissive...
4.
Stone D, Meumann N, Kuhlmann A, Peterson C, Xie H, Roychoudhury P, et al.
Hepatol Commun
. 2023 Apr;
7(2):e0009.
PMID: 37074875
Background And Aims: Adeno-associated virus (AAV) vectors are widely used to deliver therapeutic transgenes to distinct tissues, including the liver. Vectors based on naturally occurring AAV serotypes as well as...
5.
Addetia A, Lieberman N, Phung Q, Hsiang T, Xie H, Roychoudhury P, et al.
mBio
. 2021 Apr;
12(2).
PMID: 33849972
RNA viruses that replicate in the cytoplasm often disrupt nucleocytoplasmic transport to preferentially translate their own transcripts and prevent host antiviral responses. The accessory protein ORF6 has previously been shown...
6.
Stone D, Long K, Loprieno M, De Silva Feelixge H, Kenkel E, Liley R, et al.
Mol Ther Methods Clin Dev
. 2021 Jan;
20:258-275.
PMID: 33473359
Chronic hepatitis B virus (HBV) infection is a major public health problem. New treatment approaches are needed because current treatments do not target covalently closed circular DNA (cccDNA), the template...
7.
Stone D, Kenkel E, Loprieno M, Tanaka M, De Silva Feelixge H, Kumar A, et al.
Hum Gene Ther
. 2020 Oct;
32(1-2):96-112.
PMID: 32998579
Adeno-associated virus (AAV) vectors such as AAV6, which shows tropism for primary human CD4 T cells , are being explored for delivery of anti-HIV therapeutic modalities . However, pre-existing immunity...
8.
Aubert M, Strongin D, Roychoudhury P, Loprieno M, Haick A, Klouser L, et al.
Nat Commun
. 2020 Aug;
11(1):4148.
PMID: 32811834
We evaluate gene editing of HSV in a well-established mouse model, using adeno-associated virus (AAV)-delivered meganucleases, as a potentially curative approach to treat latent HSV infection. Here we show that...
9.
Perchetti G, Nalla A, Huang M, Zhu H, Wei Y, Stensland L, et al.
J Clin Virol
. 2020 May;
128:104438.
PMID: 32405257
Background: Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has caused considerable disruption across the world, resulting in more than 235,000 deaths since December 2019. SARS-CoV-2 has a wide tropism and...
10.
Dang C, Aubert M, De Silva Feelixge H, Diem K, Loprieno M, Roychoudhury P, et al.
Sci Rep
. 2017 Apr;
7(1):927.
PMID: 28424485
The ability to genetically manipulate trigeminal ganglion (TG) neurons would be useful in the study of the craniofacial nervous system and latent alphaherpesvirus infections. We investigated adeno-associated virus (AAV) vectors...