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Michelino De Laurentiis

Explore the profile of Michelino De Laurentiis including associated specialties, affiliations and a list of published articles. Areas
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Articles 145
Citations 4153
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Recent Articles
11.
Molinelli C, Bruzzone M, Blondeaux E, Ruelle T, Lanzavecchia C, De Laurentiis M, et al.
Eur J Cancer . 2024 Nov; 213():115113. PMID: 39536433
Purpose: The aim of this study was to evaluate the effectiveness of CDK 4/6 inhibitors (CDK 4-6i) according to HER2 status (low/zero), and endocrine resistance/sensitivity, as well as the efficacy...
12.
Bardia A, Jhaveri K, Im S, Pernas S, De Laurentiis M, Wang S, et al.
J Clin Oncol . 2024 Sep; 43(3):285-296. PMID: 39265124
Purpose: The global, phase 3, open-label, randomized TROPION-Breast01 study assessed the trophoblast cell surface antigen 2-directed antibody-drug conjugate datopotamab deruxtecan (Dato-DXd) versus investigator's choice of chemotherapy (ICC) in hormone receptor-positive/human...
13.
Pagliuca M, Havas J, Thomas E, Drouet Y, Soldato D, Franzoi M, et al.
J Natl Cancer Inst . 2024 Sep; 117(1):89-102. PMID: 39250750
Background: Fatigue, cognitive impairment, anxiety, depression, and sleep disturbance are cancer-related behavioral symptoms that may persist years after early-stage breast cancer, affecting quality of life. We aimed to generate a...
14.
Zambelli A, Cortesi L, Gaudio M, Arpino G, Bianchini G, Caruso F, et al.
Cancer Treat Rev . 2024 Aug; 130:102815. PMID: 39208751
The introduction of PARP inhibitors has revolutionized the management and treatment of patients with pathogenic germline variants of BRCA1/2 who have developed breast cancer. The implementation of PARP inhibitors in...
15.
Scagnoli S, Pisegna S, Toss A, Caputo R, De Laurentiis M, Palleschi M, et al.
NPJ Breast Cancer . 2024 Aug; 10(1):68. PMID: 39095493
No abstract available.
16.
Hamilton E, Ma C, De Laurentiis M, Iwata H, Hurvitz S, Wander S, et al.
Future Oncol . 2024 Jul; 20(32):2447-2455. PMID: 39072356
Vepdegestrant (ARV-471) is an oral PROTAC ER degrader that binds an E3 ubiquitin ligase and ER to directly trigger ubiquitination of ER and its subsequent proteasomal degradation. In a first-in-human...
17.
Porciello G, Coluccia S, Vitale S, Palumbo E, Luongo A, Grimaldi M, et al.
Cancers (Basel) . 2024 Jul; 16(14). PMID: 39061215
Health-related quality of life (HRQoL) represents one of the most concerning aspects for cancer patients. The Healthy Eating Index (HEI) is an a priori diet quality index directly associated with...
18.
Caminiti C, Maglietta G, Arenare L, Di Liello R, Migliaccio G, Barberio D, et al.
Breast . 2024 Jul; 77:103781. PMID: 39059033
Patients' self-reporting is increasingly considered essential to measure quality-of-life and treatment-related side-effects. However, if multiple patient-reported instruments are used, redundancy may represent an overload for patients. Patient-Reported Outcomes Common Terminology...
19.
Tinterri C, Gentile D, Caruso F, Cortesi L, De Laurentiis M, Fortunato L, et al.
Curr Oncol . 2024 Jul; 31(7):3815-3825. PMID: 39057154
Background: Breast units (BUs) provide breast cancer (BC) care, including prevention, treatment, and genetic assessment. Genetic research has highlighted BRCA1/2 mutations as key hereditary BC risk factors. BRCA testing is...
20.
Scagnoli S, Pisegna S, Toss A, Caputo R, De Laurentiis M, Palleschi M, et al.
NPJ Breast Cancer . 2024 Jul; 10(1):58. PMID: 39019916
Abemaciclib demonstrated clinical benefit in women affected by HR+/HER2- advanced breast cancer (aBC). Drug-drug interactions (DDIs) can lead to reduced treatment efficacy or increased toxicity. This retro-prospective study aimed to...