Michele Kyle
Overview
Explore the profile of Michele Kyle including associated specialties, affiliations and a list of published articles.
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16
Citations
98
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Recent Articles
1.
Ren X, He J, Li S, Hu H, Kyle M, Kohsaka S, et al.
Int J Mol Sci
. 2024 Aug;
25(16).
PMID: 39201584
Monocytes are circulating macrophage precursors generated from bone marrow hematopoietic stem cells. In adults, monocytes continuously replenish cerebral border-associated macrophages under physiological conditions. Monocytes also rapidly infiltrate the brain in...
2.
Gardner R, Kyle M, Hughes K, Zhao L
Biomolecules
. 2024 Jul;
14(7).
PMID: 39062541
Alzheimer's disease (AD) leads to progressive neurodegeneration and dementia. AD primarily affects older adults with neuropathological changes including amyloid-beta (Aβ) deposition, neuroinflammation, and neurodegeneration. We have previously demonstrated that systemic...
3.
Gardner R, Kyle M, Hughes K, Zhao L
bioRxiv
. 2024 May;
PMID: 38766064
Alzheimers disease leads to progressive neurodegeneration and dementia. Alzheimers disease primarily affects older adults with neuropathological changes including amyloid beta deposition, neuroinflammation, and neurodegeneration. We have previously demonstrated that systemic...
4.
Qiu X, Ping S, Kyle M, Chin L, Zhao L
Cells
. 2023 Mar;
12(5).
PMID: 36899841
Severe traumatic brain injury (TBI) causes long-term disability and death in young adults. White matter is vulnerable to TBI damage. Demyelination is a major pathological change of white matter injury...
5.
Qiu X, Ping S, Kyle M, Chin L, Zhao L
bioRxiv
. 2023 Feb;
PMID: 36747858
Severe traumatic brain injury (TBI) causes long-term disability and death in young adults. White matter is vulnerable to TBI damage. Demyelination is a major pathological change of white matter injury...
6.
Qiu X, Ping S, Kyle M, Chin L, Zhao L
Acta Neuropathol Commun
. 2021 Apr;
9(1):63.
PMID: 33832542
Traumatic brain injury (TBI) is a major cause of long-term disability in young adults. An evidence-based treatment for TBI recovery, especially in the chronic phase, is not yet available. Using...
7.
Ping S, Qiu X, Kyle M, Zhao L
Aging Dis
. 2021 Feb;
12(1):72-92.
PMID: 33532129
Chemokine (C-C motif) receptor 5 (CCR5) is expressed not only in the immune cells but also in cerebral cells such as neurons, glia, and vascular cells. Stroke triggers high expression...
8.
He J, Russell T, Qiu X, Hao F, Kyle M, Chin L, et al.
Brain Res
. 2020 Jun;
1746:147000.
PMID: 32579949
Traumatic brain injury (TBI) is a major cause of death and disability in young adults worldwide. TBI-induced long-term cognitive deficits represent a growing clinical problem. Stem cell factor (SCF) and...
9.
Qiu X, Ping S, Kyle M, Chin L, Zhao L
Exp Neurol
. 2020 May;
330:113335.
PMID: 32360282
Severe traumatic brain injury (TBI) is the major cause of long-term, even life-long disability and cognitive impairments in young adults. The lack of therapeutic approaches to improve recovery in the...
10.
Qiu X, Ping S, Kyle M, Longo J, Chin L, Zhao L
J Neurotrauma
. 2019 Oct;
37(7):950-965.
PMID: 31621496
S100 calcium-binding protein A9 (S100a9), a proinflammatory protein, has been shown to be involved in the development of neuroinflammatory disorders and neurodegenerative diseases. Upregulation of S100a9 in the brain during...