Michela Roccuzzo
Overview
Explore the profile of Michela Roccuzzo including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
185
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Recent Articles
1.
Gurrieri E, Carradori G, Roccuzzo M, Pancher M, Peroni D, Belli R, et al.
J Biomed Sci
. 2024 Oct;
31(1):92.
PMID: 39402557
Background: Extracellular vesicles (EVs) are cell-secreted particles conceived as natural vehicles for intercellular communication. The capacity to entrap heterogeneous molecular cargoes and target specific cell populations through EV functionalization promises...
2.
Assuncao Carreira A, Ravera S, Zucal C, Thongon N, Caffa I, Astigiano C, et al.
Neoplasia
. 2023 May;
41:100903.
PMID: 37148658
Nicotinamide phosphoribosyltransferase (NAMPT) is a key metabolic enzyme in NAD synthesis pathways and is found upregulated in several tumors, depicting NAD(H) lowering agents, like the NAMPT inhibitor FK866, as an...
3.
Migazzi A, Scaramuzzino C, Anderson E, Tripathy D, Hernandez I, Grant R, et al.
Cell Rep
. 2021 Apr;
35(2):108980.
PMID: 33852844
The huntingtin (HTT) protein transports various organelles, including vesicles containing neurotrophic factors, from embryonic development throughout life. To better understand how HTT mediates axonal transport and why this function is...
4.
Burigotto M, Mattivi A, Migliorati D, Magnani G, Valentini C, Roccuzzo M, et al.
EMBO J
. 2020 Dec;
40(4):e104844.
PMID: 33350486
Centrosome amplification results into genetic instability and predisposes cells to neoplastic transformation. Supernumerary centrosomes trigger p53 stabilization dependent on the PIDDosome (a multiprotein complex composed by PIDD1, RAIDD and Caspase-2),...
5.
Idilli A, Pazzi C, Dal Pozzolo F, Roccuzzo M, Mione M
Genes (Basel)
. 2020 Dec;
11(12).
PMID: 33266037
Cohesin is a protein complex consisting of four core subunits responsible for sister chromatid cohesion in mitosis and meiosis, and for 3D genome organization and gene expression through the establishment...
6.
Corradi E, Dalla Costa I, Gavoci A, Iyer A, Roccuzzo M, Otto T, et al.
EMBO J
. 2020 Feb;
39(6):e102513.
PMID: 32073171
Various species of non-coding RNAs (ncRNAs) are enriched in specific subcellular compartments, but the mechanisms orchestrating their localization and their local functions remain largely unknown. We investigated both aspects using...
7.
Cutarelli A, Ghio S, Zasso J, Speccher A, Scarduelli G, Roccuzzo M, et al.
Cells
. 2020 Jan;
9(1).
PMID: 31905823
Silicon is a promising material for tissue engineering since it allows to produce micropatterned scaffolding structures resembling biological tissues. Using specific fabrication methods, it is possible to build aligned 3D...
8.
Bellon A, Iyer A, Bridi S, Lee F, Ovando-Vazquez C, Corradi E, et al.
Cell Rep
. 2017 Feb;
18(5):1171-1186.
PMID: 28147273
During brain wiring, cue-induced axon behaviors such as directional steering and branching are aided by localized mRNA translation. Different guidance cues elicit translation of subsets of mRNAs that differentially regulate...
9.
Roccuzzo M, Visintin C, Tili F, Visintin R
Nat Cell Biol
. 2015 Feb;
17(3):251-61.
PMID: 25706236
Cleavage of cohesins and cyclin-dependent kinase (CDK) inhibition are thought to be sufficient for triggering chromosome segregation. Here we identify an essential requirement for anaphase chromosome movement. We show that,...