Michel Simonneau
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Explore the profile of Michel Simonneau including associated specialties, affiliations and a list of published articles.
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42
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972
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Recent Articles
21.
Lepagnol-Bestel A, Dubertret C, Benmessaoud D, Simonneau M, Ades J, Kacha F, et al.
Psychiatr Genet
. 2010 May;
20(6):298-303.
PMID: 20505556
Objective: The Disrupted-in-Schizophrenia-1 (DISC1) gene is a promising genetic risk factor for major mental illnesses, especially schizophrenia. Several variants encompassing the DISC1 gene have been associated with schizophrenia and specific...
22.
Loe-Mie Y, Lepagnol-Bestel A, Maussion G, Doron-Faigenboim A, Imbeaud S, Delacroix H, et al.
Hum Mol Genet
. 2010 May;
19(14):2841-57.
PMID: 20457675
The SMARCA2 gene, which encodes BRM in the SWI/SNF chromatin-remodeling complex, was recently identified as being associated with schizophrenia (SZ) in a genome-wide approach. Polymorphisms in SMARCA2, associated with the...
23.
Lepagnol-Bestel A, Zvara A, Maussion G, Quignon F, Ngimbous B, Ramoz N, et al.
Hum Mol Genet
. 2009 Feb;
18(8):1405-14.
PMID: 19218269
The molecular mechanisms that lead to the cognitive defects characteristic of Down syndrome (DS), the most frequent cause of mental retardation, have remained elusive. Here we use a transgenic DS...
24.
Laroche F, Ramoz N, Leroy S, Fortin C, Rousselot-Paillet B, Philippe A, et al.
Psychiatr Genet
. 2008 Nov;
18(6):295-301.
PMID: 19018235
Objectives: Autism (MIM#209850) and schizophrenia (MIM#181500) are both neurodevelopmental psychiatric disorders characterized by a highly genetic component. Homeogenes and forkhead genes encode transcription factors, which have been involved in brain...
25.
Maussion G, Carayol J, Lepagnol-Bestel A, Tores F, Loe-Mie Y, Milbreta U, et al.
Hum Mol Genet
. 2008 May;
17(16):2541-51.
PMID: 18492799
Autism spectrum disorders (ASDs) are common, heritable, but genetically heterogeneous neurodevelopmental conditions. We recently defined a susceptibility locus for ASDs on chromosome 1q41-q42. High-resolution single-nucleotide polymorphisms (126 SNPs) genotyping across...
26.
Kelai S, Maussion G, Noble F, Boni C, Ramoz N, Moalic J, et al.
Neuroreport
. 2008 Apr;
19(7):751-5.
PMID: 18418251
Dysfunctions affecting the connections of basal ganglia lead to major neurological and psychiatric disorders. We investigated levels of mRNA for three neurexins (Nrxn) and three neuroligins (Nlgn) in the globus...
27.
Davidovic L, Jaglin X, Lepagnol-Bestel A, Tremblay S, Simonneau M, Bardoni B, et al.
Hum Mol Genet
. 2007 Sep;
16(24):3047-58.
PMID: 17881655
Fragile X mental retardation 1 protein (FMRP) is an RNA-binding protein whose absence results in the fragile X syndrome, the most common inherited form of mental retardation. FMRP contains multiple...
28.
Lepagnol-Bestel A, Maussion G, Ramoz N, Moalic J, Gorwood P, Simonneau M
Neuroreport
. 2007 May;
18(5):441-6.
PMID: 17496800
Neurite outgrowth involves various molecular mechanisms generating complex brain connections. These mechanisms have been linked to plasticity and learning and are thought to be deregulated in neuropsychiatric diseases. The transcription...
29.
Mas C, Guimiot-Maloum I, Guimiot F, Khelfaoui M, Nepote V, Bourgeois F, et al.
Gene Expr Patterns
. 2005 May;
5(5):577-85.
PMID: 15908283
Neocortical neurons are generated predominantly from the cells that proliferate in the ventricular zone of the telencephalon. In order to understand the nature of these expanding cortical neuronal progenitor cells,...
30.
Al Halabiah H, Delezoide A, Cardona A, Moalic J, Simonneau M
Gene Expr Patterns
. 2005 Mar;
5(4):561-8.
PMID: 15749087
Nogo protein has been identified as the component of central nervous system (CNS) myelin that limits axonal regeneration. We investigated the expression of the genes encoding Nogo and its receptor,...