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Michel Mandro

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Citations 390
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Recent Articles
1.
Hedtke S, Choi Y, Kode A, Chalasani G, Sirwani N, Jada S, et al.
Pathogens . 2023 Jul; 12(7). PMID: 37513818
Onchocerciasis is a neglected tropical disease targeted for elimination using ivermectin mass administration. Ivermectin kills the microfilariae and temporarily arrests microfilariae production by the macrofilariae. We genotyped 436 microfilariae from...
2.
Post R, Laudisoit A, Mandro M, Lakwo T, Laemmer C, Pfarr K, et al.
PLoS Negl Trop Dis . 2022 Nov; 16(11):e0010684. PMID: 36331979
Background: The objective of this study was to characterise the vector in a small hyper-endemic focus of onchocerciasis (the Kakoi-Koda focus) which has recently been discovered on the western slopes...
3.
Hotterbeekx A, Vieri M, Ramberger M, Jozefzoon-Aghai A, Mandro M, Tepage F, et al.
Pathogens . 2021 Aug; 10(7). PMID: 34357995
Nodding syndrome has been suggested to be triggered by neurotoxic leiomodin-1 auto-antibodies cross-reacting with . Here, we screened serum and CSF samples of persons with nodding syndrome and other forms...
4.
Roach M, Cantu A, Vieri M, Cotten M, Kellam P, Phan M, et al.
Pathogens . 2021 Jul; 10(7). PMID: 34206564
Despite the increasing epidemiological evidence that the parasite is strongly associated with epilepsy in children, hence the name onchocerciasis-associated epilepsy (OAE), the pathophysiological mechanism of OAE remains to be elucidated....
5.
Vieri M, Hotterbeekx A, Mandro M, Fodjo J, Dusabimana A, Nyisi F, et al.
Pathogens . 2021 Jul; 10(6). PMID: 34201076
Onchocerciasis-associated epilepsy (OAE) is a devastating childhood disorder occurring in areas with high transmission. Despite epidemiological evidence showing the association between and epilepsy, the underlying mechanism remains unknown. Since high...
6.
Vieri M, Mandro M, Cardellino C, Orza P, Ronzoni N, Fodjo J, et al.
Pathogens . 2021 Apr; 10(3). PMID: 33803565
A high burden of epilepsy is observed in Africa where parasitological infections are endemic. In 2016, in an Onchocerciasis endemic area in the Logo health zone, in Ituri province in...
7.
Dusabimana A, Bhwana D, Mandro M, Mmbando B, Fodjo J, Colebunders R
Pathogens . 2020 Oct; 9(10). PMID: 33081184
There is growing epidemiological evidence that onchocerciasis may induce epilepsy. High prevalence of onchocerciasis has been reported in onchocerciasis-meso and hyper-endemic regions. We aimed to determine the OV16 antibody prevalence...
8.
Dusabimana A, Bhwana D, Raimon S, Mmbando B, Hotterbeekx A, Tepage F, et al.
Pathogens . 2020 Aug; 9(8). PMID: 32751060
Despite a long history of community-directed treatment with ivermectin (CDTI), a high ongoing transmission is observed in certain onchocerciasis-endemic regions in Africa with a high prevalence of epilepsy. We investigated...
9.
Hotterbeekx A, Perneel J, Mandro M, Abhafule G, Fodjo J, Dusabimana A, et al.
Pathogens . 2020 Jun; 9(6). PMID: 32498284
Onchocerciasis is diagnosed by detecting microfilariae in skin snips or by detecting OV16 IgG4 antibodies in blood by either enzyme linked immunosorbent assay (ELISA) or a rapid diagnostic test (RDT)....
10.
Mandro M, Fodjo J, Dusabimana A, Mukendi D, Haesendonckx S, Lokonda R, et al.
Pathogens . 2020 Mar; 9(3). PMID: 32164367
Background: There is anecdotal evidence that ivermectin may decrease seizure frequency in -infected persons with epilepsy (PWE). Methods: In October 2017, a 12-month clinical trial was initiated in rural Democratic...