Michel Flesch
Overview
Explore the profile of Michel Flesch including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
705
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0
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Recent Articles
1.
Maynadie M, Girodon F, Manivet-Janoray I, Mounier M, Mugneret F, Bailly F, et al.
Haematologica
. 2010 Oct;
96(1):55-61.
PMID: 20971817
Background: Epidemiological data on myeloid malignancies are very rare in the literature due to a lack of registration by cancer registries until 2000. The Registry of Hematologic Malignancies of the...
2.
Etienne-Grimaldi M, Milano G, Maindrault-Goebel F, Chibaudel B, Formento J, Francoual M, et al.
Br J Clin Pharmacol
. 2010 Jan;
69(1):58-66.
PMID: 20078613
What Is Already Known About This Subject: * Numerous clinical studies, including a few prospective ones, have reported conflicting results on the impact of gene polymorphisms related to fluorouracil (FU)...
3.
Chibaudel B, Maindrault-Goebel F, Lledo G, Mineur L, Andre T, Bennamoun M, et al.
J Clin Oncol
. 2009 Sep;
27(34):5727-33.
PMID: 19786657
Purpose: This study compared chemotherapy discontinuation with maintenance therapy with leucovorin and fluorouracil after six cycles of folinic acid, fluorouracil, and oxaliplatin (FOLFOX) chemotherapy in the first-line treatment of metastatic...
4.
Figer A, Perez-Staub N, Carola E, Tournigand C, Lledo G, Flesch M, et al.
Cancer
. 2007 Oct;
110(12):2666-71.
PMID: 17963264
Background: Patients older than 75 years of age are usually excluded from metastatic colorectal cancer randomized studies. The OPTIMOX1 study evaluated FOLFOX7, a simplified (s) leucovorin (LV) and 5-fluorouracil (5FU)...
5.
Andre T, Quinaux E, Louvet C, Colin P, Gamelin E, Bouche O, et al.
J Clin Oncol
. 2007 Aug;
25(24):3732-8.
PMID: 17704423
Purpose: This randomized, 2 x 2 factorial study compared a semimonthly regimen (fluorouracil [FU] and leucovorin [LV] semi-monthly is LV5FU2) with a monthly regimen of FU and LV (mFU/LV) as...
6.
De Gramont A, Buyse M, Abrahantes J, Burzykowski T, Quinaux E, Cervantes A, et al.
J Clin Oncol
. 2007 Aug;
25(22):3224-9.
PMID: 17664470
Purpose: In the OPTIMOX1 trial, previously untreated patients with advanced colorectal cancer were randomly assigned to two different schedules of leucovorin, fluorouracil, and oxaliplatin that were administered until progression in...
7.
Molucon-Chabrot C, Isambert N, Benoit L, Zanetta S, Fraisse J, Guilland J, et al.
Anticancer Drugs
. 2006 Nov;
17(10):1211-7.
PMID: 17075321
Intraperitoneal epinephrine above 1 mg/l concentration has been shown to enhance the intratumoral accumulation and antitumor activity of intraperitoneal cisplatin in rats with advanced peritoneal carcinomatosis. The aim of this...
8.
Abgrall J, Guibaud I, Bastie J, Flesch M, Rossi J, Lacotte-Thierry L, et al.
Haematologica
. 2006 Aug;
91(8):1027-32.
PMID: 16885042
Background And Objectives: In non-randomized studies, thalidomide appeared to be effective in myeloid metaplasia with myelofibrosis (MMM). We compared thalidomide to placebo for treatment of anemia in MMM. Design And...
9.
Hebbar M, Tournigand C, Lledo G, Mabro M, Andre T, Louvet C, et al.
Cancer Invest
. 2006 Mar;
24(2):154-9.
PMID: 16537184
We assessed a schedule alternating 4 FOLFOX and 4 FOLFIRI cycles in 39 patients with 5-FU resistant metastatic colorectal cancer. Patients alternatively received 4 FOLFOX-6 cycles (oxaliplatin 100 mg/m(2), leucovorin...
10.
Faivre L, Meerpohl J, Da Costa L, Marie I, Nouvel C, Gnekow A, et al.
Haematologica
. 2006 Mar;
91(4):530-3.
PMID: 16537118
We reviewed 64 pregnancies in 26 women with Diamond-Blackfan anemia (DBA) included in the French and German DBA registries. Complications were seen in 42 pregnancies (66%) and included abortion, pre-eclampsia,...