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Michel Farnier

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Articles 137
Citations 3613
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Recent Articles
11.
Ferrieres J, Farnier M, Bruckert E, Vimont A, Durlach V, Ferrari E, et al.
Atheroscler Plus . 2023 Jan; 50:17-24. PMID: 36643794
Background And Aims: Heterozygous familial hypercholesterolemia (HeFH) is increasingly better diagnosed and treatments can improve the cardiovascular prognosis. We evaluated the long-term cardiovascular risk of HeFH using the French REgistry...
12.
Henry P, Cariou B, Farnier M, Lakhdari S, Detournay B
Arch Cardiovasc Dis . 2022 Dec; 116(1):3-8. PMID: 36535853
Background: Recently, a multicentre, prospective, single-arm, phase 3b, open-label trial was conducted to determine the safety and efficacy of alirocumab, a proprotein convertase subtilisin/kexin type 9 inhibitor, in a real-life...
13.
Farnier M, Santos R, Cosin-Sales J, Ezhov M, Liu J, Granados D, et al.
Eur J Prev Cardiol . 2022 Sep; 29(17):2264-2271. PMID: 36134461
Aims: The 2019 European Society of Cardiology/European Atherosclerosis Society (ESC/EAS) dyslipidaemia guidelines recommend achievement of low-density lipoprotein cholestrol (LDL-C) goals based on an individual's risk. We aimed to evaluate the...
14.
Peretti N, Vimont A, Mas E, Ferrieres J, Tounian P, Lemale J, et al.
J Pediatr . 2022 Sep; 253:18-24.e2. PMID: 36049522
Objective: To identify childhood and parental factors associated with initiation of statin therapy in children with heterozygous familial hypercholesterolemia (HeFH), including underlying genetic diagnosis or parental premature atherosclerotic cardiovascular disease...
15.
Farnier M, Chague F, Maza M, Bichat F, Masson D, Cottin Y, et al.
J Clin Lipidol . 2022 Aug; 16(5):685-693. PMID: 35995726
Background: Lipoprotein(a) (Lp(a)) is a well-recognized independent risk factor for atherosclerotic cardiovascular disease (ASCVD). However, limited data are available on the relationship between coronary artery disease (CAD) burden and Lp(a)...
16.
Eid P, Arnould L, Gabrielle P, Aho L, Farnier M, Creuzot-Garcher C, et al.
J Pers Med . 2022 Jun; 12(6). PMID: 35743656
Familial hypercholesterolemia (FH) is a common but underdiagnosed genetic disorder affecting cholesterol metabolism, leading to atherosclerotic disease. The relationship between retinal microvascular changes and the presence of atheroma in patients...
17.
Ghaleb Y, Elbitar S, Philippi A, Khoury P, Azar Y, Andrianirina M, et al.
Metabolites . 2022 Mar; 12(3). PMID: 35323704
Autosomal Dominant Hypercholesterolemia (ADH) is a genetic disorder caused by pathogenic variants in , , and genes. We sought to identify new candidate genes responsible for the ADH phenotype in...
18.
Ferrieres J, Roubille F, Farnier M, Jourdain P, Angoulvant D, Boccara F, et al.
J Clin Med . 2021 Dec; 10(24). PMID: 34945235
Introduction: Patients with established coronary artery disease (CAD) are at very high risk for cardiovascular events. Methods: The DAUSSET study is a national, multicenter, non-interventional study that included very high-risk...
19.
Durlach V, Bonnefont-Rousselot D, Boccara F, Varret M, Di-Filippo Charcosset M, Cariou B, et al.
Arch Cardiovasc Dis . 2021 Nov; 114(12):828-847. PMID: 34840125
Lipoprotein(a) is an apolipoprotein B100-containing low-density lipoprotein-like particle that is rich in cholesterol, and is associated with a second major protein, apolipoprotein(a). Apolipoprotein(a) possesses structural similarity to plasminogen but lacks...
20.
Reach G, Benarbia L, Bruckert E, Kevorkian J, Farnier M, Mourad J, et al.
Patient Prefer Adherence . 2021 Aug; 15:1739-1753. PMID: 34408407
Purpose: Some patients make a rational choice not to follow medical prescriptions; others fail to take their medications for reasons beyond their control, such as mere forgetfulness or a weak...