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Michel Drouet

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Citations 540
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Recent Articles
1.
Rota Graziosi E, Francois S, Nasser F, Gauthier M, Oger M, Favier A, et al.
Radiat Res . 2024 Jan; 201(5):429-439. PMID: 38253061
The current geopolitical context has brought the radiological nuclear risk to the forefront of concerns. High-dose localized radiation exposure leads to the development of a musculocutaneous radiation syndrome affecting the...
2.
Schwanke D, Valente M, Ostheim P, Schule S, Bobyk L, Drouet M, et al.
Int J Radiat Biol . 2024 Jan; 100(4):527-540. PMID: 38227483
Purpose: In a previous baboon-study, a total of 29 genes were identified for clinical outcome prediction of the hematologic, acute, radiation, syndrome (H-ARS) severity. Among them, four genes ( appeared...
3.
Drouet M, Le Bourhis E
Materials (Basel) . 2023 Jul; 16(13). PMID: 37445022
Metallic alloys are, by essence, ductile and stiff and can support loads without sudden rupture. This ductility becomes a disadvantage when applications require wear resistance. In this case, the hardening...
4.
Restier-Verlet J, Drouet M, Pras P, Ferlazzo M, Granzotto A, Sonzogni L, et al.
Biomolecules . 2023 Mar; 13(3). PMID: 36979459
The radiation protection strategy with chemical agents has long been based on an antioxidative approach consisting in reducing the number of radical oxygen and nitrogen species responsible for the formation...
5.
Parry V, Le Bourhis E, Pichon L, Drouet M
Materials (Basel) . 2022 Dec; 15(24). PMID: 36556838
Surface treatments of Ti-6Al-4V alloys are of utmost importance for biomedical applications since they allow for tribological gain. Here, Ti-6Al-4V disks have been PBII nitrided at either 500, 600, 700...
6.
Helissey C, Guitard N, Thery H, Goulinet S, Mauduit P, Girleanu M, et al.
Biology (Basel) . 2022 Sep; 11(7). PMID: 36101361
Radiation cystitis (RC) results from chronic inflammation, fibrosis, and vascular damage. The urinary symptoms it causes have a serious impact on patients' quality of life. Despite the improvement in irradiation...
7.
Boittin F, Beddek K, Thery H, Pateux J, Cosler G, Riccobono D, et al.
Biochem Biophys Res Commun . 2022 Mar; 602:127-134. PMID: 35272142
The immunosuppressant drug Cyclosporin A (CsA) has been widely used to prevent the development of Graft-versus-Host Disease (GvHD) that can occur after transplantation, including allogeneic graft after accidental high-dose irradiation...
8.
Farese A, Drouet M, Herodin F, Bertho J, Thrall K, Authier S, et al.
Health Phys . 2021 Sep; 121(4):304-330. PMID: 34546214
Medical countermeasure development under the US Food and Drug Administration animal rule requires validated animal models of acute radiation effects. The key large animal model is the non-human primate, rhesus...
9.
Francois S, Helissey C, Cavallero S, Drouet M, Libert N, Cosset J, et al.
Front Pharmacol . 2021 Jun; 12:640040. PMID: 34113249
The evolution of SARS-CoV-2 pneumonia to acute respiratory distress syndrome is linked to a virus-induced "cytokine storm", associated with systemic inflammation, coagulopathies, endothelial damage, thrombo-inflammation, immune system deregulation and disruption...
10.
Nikovics K, Favier A, Barbier L, Drouet M, Riccobono D
Cytokine . 2020 Oct; 137:155318. PMID: 33045525
Macrophages play a fundamental role in the different stages of muscle regeneration although the precise mechanisms involved are not entirely understood. Here we investigated the types of macrophages and cytokines...