Michal Smahel
Overview
Explore the profile of Michal Smahel including associated specialties, affiliations and a list of published articles.
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Articles
46
Citations
280
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Recent Articles
1.
Smahel M, Johari S, Smahelova J, Pfeiferova L, Nunvar J
Cancer Sci
. 2024 Dec;
116(3):622-632.
PMID: 39624899
Cancer immunotherapy is increasingly used in clinical practice, but its success rate is reduced by tumor escape from the immune system. This may be due to the genetic instability of...
2.
Bohacek V, Erbenova T, Malina J, Kloubcova M, Smahel M, Eigner V, et al.
RSC Adv
. 2024 Nov;
14(50):37370-37379.
PMID: 39575379
Three series of spiropyran photoswitches with an auxiliary chiral centre at position 3' of the indoline unit were synthesized. Using one example, a novel methodology for synthesis of an optically...
3.
Smahelova J, Pokryvkova B, Stovickova E, Grega M, Vencalek O, Smahel M, et al.
Infect Agent Cancer
. 2024 Jun;
19(1):26.
PMID: 38858774
Background: A proportion of head and neck carcinomas (HNSCCs) are induced by high-risk human papillomaviruses (HPVs) and are associated with better patient outcomes compared to patients with HNSCCs related to...
4.
Kanwal M, Polakova I, Olsen M, Kasi M, Tachezy R, Smahel M
J Cancer
. 2024 May;
15(11):3466-3480.
PMID: 38817852
: Cancer development involves alterations in key cellular pathways, with aspartate β-hydroxylase (ASPH) emerging as an important player in tumorigenesis. ASPH is upregulated in various cancer types, where it promotes...
5.
Vranova L, Polakova I, Vanikova S, Salakova M, Musil J, Vanickova M, et al.
Infect Dis (Lond)
. 2024 May;
56(10):851-869.
PMID: 38805304
Background: SARS-CoV-2, which causes COVID-19, has killed more than 7 million people worldwide. Understanding the development of postinfectious and postvaccination immune responses is necessary for effective treatment and the introduction...
6.
Kanwal M, Smahelova J, Ciharova B, Johari S, Nunvar J, Olsen M, et al.
J Cancer
. 2024 Feb;
15(5):1138-1152.
PMID: 38356711
Overexpression of aspartate β-hydroxylase (ASPH) in human tumors contributes to their progression by stimulating cell proliferation, migration, and invasion. Several signaling pathways affected by ASPH have been identified, but the...
7.
Smahel M, Nunvar J
Virol J
. 2023 Dec;
20(1):287.
PMID: 38049810
Background: Human papillomaviruses (HPVs) induce a subset of head and neck squamous cell carcinomas (HNSCC) and anogenital cancers, particularly cervical cancer (CC). The major viral proteins that contribute to tumorigenesis...
8.
Poryvai A, Smahel M, Svecova M, Nemati A, Shadpour S, Ulbrich P, et al.
ACS Nano
. 2022 Jul;
16(8):11833-11841.
PMID: 35867644
Nanoparticles serving as a multifunctional and multiaddressable dopant to modify the properties of liquid crystalline matrices are developed by combining cobalt ferrite nanocrystals with organic ligands featuring a robust photosensitive...
9.
Piatakova A, Polakova I, Smahelova J, Johari S, Nunvar J, Smahel M
Cancers (Basel)
. 2021 Jul;
13(12).
PMID: 34205330
Tumor-associated macrophages (TAMs) plentifully infiltrate the tumor microenvironment (TME), but their role in anti-tumor immunity is controversial. Depending on the acquired polarization, they can either support tumor growth or participate...
10.
Vackova J, Polakova I, Johari S, Smahel M
Cancers (Basel)
. 2021 Apr;
13(8).
PMID: 33923750
Cluster of differentiation (CD) 80 is mainly expressed in immune cells but can also be found in several types of cancer cells. This molecule may either activate or inhibit immune...