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Michal J Gajda

Explore the profile of Michal J Gajda including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 467
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Recent Articles
1.
Rauscher S, Gapsys V, Gajda M, Zweckstetter M, de Groot B, Grubmuller H
J Chem Theory Comput . 2015 Nov; 11(11):5513-24. PMID: 26574339
Intrinsically disordered proteins (IDPs) are notoriously challenging to study both experimentally and computationally. The structure of IDPs cannot be described by a single conformation but must instead be described as...
2.
Arpino J, Czapinska H, Piasecka A, Edwards W, Barker P, Gajda M, et al.
J Am Chem Soc . 2012 Jul; 134(33):13632-40. PMID: 22822710
The construction of useful functional biomolecular components not currently part of the natural repertoire is central to synthetic biology. A new light-capturing ultra-high-efficiency energy transfer protein scaffold has been constructed...
3.
Grela P, Gajda M, Armache J, Beckmann R, Krokowski D, Svergun D, et al.
Biochem J . 2012 Mar; 444(2):205-9. PMID: 22458705
The ribosomal stalk of the 60S subunit has been shown to play a crucial role in all steps of protein synthesis, but its structure and exact molecular function remain an...
4.
Gajda M, Tuszynska I, Kaczor M, Bakulina A, Bujnicki J
Bioinformatics . 2010 Oct; 26(23):2986-7. PMID: 20956242
Summary: Automatic methods for macromolecular structure prediction (fold recognition, de novo folding and docking programs) produce large sets of alternative models. These large model sets often include many native-like structures,...
5.
Pawlowski M, Gajda M, Matlak R, Bujnicki J
BMC Bioinformatics . 2008 Oct; 9:403. PMID: 18823532
Background: Computational models of protein structure are usually inaccurate and exhibit significant deviations from the true structure. The utility of models depends on the degree of these deviations. A number...
6.
Gabant G, Auxilien S, Tuszynska I, Locard M, Gajda M, Chaussinand G, et al.
Nucleic Acids Res . 2006 May; 34(9):2483-94. PMID: 16687654
The tRNA:m2(2)G10 methyltransferase of Pyrococus abyssi (PAB1283, a member of COG1041) catalyzes the N2,N2-dimethylation of guanosine at position 10 in tRNA. Boundaries of its THUMP (THioUridine synthases, RNA Methyltransferases and...
7.
Dunin-Horkawicz S, Czerwoniec A, Gajda M, Feder M, Grosjean H, Bujnicki J
Nucleic Acids Res . 2005 Dec; 34(Database issue):D145-9. PMID: 16381833
MODOMICS is the first comprehensive database resource for systems biology of RNA modification. It integrates information about the chemical structure of modified nucleosides, their localization in RNA sequences, pathways of...
8.
Kosinski J, Gajda M, Cymerman I, Kurowski M, Pawlowski M, Boniecki M, et al.
Proteins . 2005 Sep; 61 Suppl 7:106-113. PMID: 16187351
In the course of CASP6, we generated models for all targets using a new version of the "FRankenstein's monster approach." Previously (in CASP5) we were able to build many very...
9.
Ye X, ONeil P, Foster A, Gajda M, Kosinski J, Kurowski M, et al.
Protein Sci . 2004 Nov; 13(12):3298-313. PMID: 15557270
Emerging high-throughput techniques for the characterization of protein and protein-complex structures yield noisy data with sparse information content, placing a significant burden on computation to properly interpret the experimental data....