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Michal Hofer

Explore the profile of Michal Hofer including associated specialties, affiliations and a list of published articles. Areas
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Articles 30
Citations 219
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Recent Articles
1.
Perecko T, Hoferova Z, Hofer M, Pereckova J, Falk M
Life Sci . 2022 Oct; 310:121106. PMID: 36272465
Aims: Limited number of agents that provide protection against hematopoietic acute radiation syndrome led us to the evaluation of nitro-oleic acid (NOOA) as a potential protector/mitigator against radiation-induced hematopoietic injury...
2.
Hofer M
Cas Lek Cesk . 2021 Jan; 159(7-8):275-280. PMID: 33445933
Many different substances with varying mechanisms of effects have been tested both in animal experiments, as well as verified in clinical studies as potential radioprotectors and mitigators of radiation damage....
3.
Hofer M, Hoferova Z, Falk M
Molecules . 2019 Nov; 24(22). PMID: 31698831
Prostaglandins and inhibitors of their synthesis (cyclooxygenase (COX) inhibitors, non-steroidal anti-inflammatory drugs) were shown to play a significant role in the regulation of hematopoiesis. Partly due to their hematopoiesis-modulating effects,...
4.
Hofer M, Hoferova Z, Falk M
Int J Mol Sci . 2017 Jun; 18(7). PMID: 28657605
In recent times, cytokines and hematopoietic growth factors have been at the center of attention for many researchers trying to establish pharmacological therapeutic procedures for the treatment of radiation accident...
5.
Hofer M, Hoferova Z, Depes D, Falk M
Molecules . 2017 May; 22(5). PMID: 28534834
The goal of combined pharmacological approaches in the treatment of the acute radiation syndrome (ARS) is to obtain an effective therapy producing a minimum of undesirable side effects. This review...
6.
Hofer M, Falk M, Komurkova D, Falkova I, Bacikova A, Klejdus B, et al.
J Med Chem . 2016 Mar; 59(7):3003-17. PMID: 26978566
Amifostine protects normal cells from DNA damage induction by ionizing radiation or chemotherapeutics, whereas cancer cells typically remain uninfluenced. While confirming this phenomenon, we have revealed by comet assay and...
7.
Hofer M, Pospisil M, Dusek L, Hoferova Z, Komurkova D
Purinergic Signal . 2014 Nov; 11(1):79-85. PMID: 25358454
Adenosine A3 receptor knockout (A3AR KO) mice and their wild-type (WT) counterparts were compared from the point of view of their abilities to survive exposures to lethal doses of γ-radiation...
8.
Falk M, Hausmann M, Lukasova E, Biswas A, Hildenbrand G, Davidkova M, et al.
Crit Rev Eukaryot Gene Expr . 2014 Jul; 24(3):225-47. PMID: 25072148
Recent groundbreaking developments in Omics and bioinformatics have generated new hope for overcoming the complexity and variability of (radio)biological systems while simultaneously shedding more light on fundamental radiobiological questions that...
9.
Falk M, Hausmann M, Lukasova E, Biswas A, Hildenbrand G, Davidkova M, et al.
Crit Rev Eukaryot Gene Expr . 2014 Jul; 24(3):205-23. PMID: 25072147
Recent ground-breaking developments in Omics have generated new hope for overcoming the complexity and variability of biological systems while simultaneously shedding more light on fundamental radiobiological questions that have remained...
10.
Hofer M, Pospisil M, Dusek L, Hoferova Z, Komurkova D
Purinergic Signal . 2014 Apr; 10(3):509-14. PMID: 24763970
The role of the adenosine A3 receptor in hematopoiesis was studied using adenosine A3 receptor knockout (A3AR KO) mice. Hematological parameters of peripheral blood and femoral bone marrow of irradiated...