Michail Doukas
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Explore the profile of Michail Doukas including associated specialties, affiliations and a list of published articles.
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91
Citations
817
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Recent Articles
1.
Wismans L, Hendriks T, Suurmeijer J, Nuyttens J, Bruynzeel A, Intven M, et al.
Br J Surg
. 2025 Feb;
112(2).
PMID: 39891429
Background: Postoperative pancreatic fistula is the main driver of morbidity and mortality after pancreatoduodenectomy. In high-risk patients, the rate of postoperative pancreatic fistula approaches 50%, whereas it is below 5%...
2.
Latacz E, Verheul S, Sillis Y, Van Dam P, Doukas M, Grunhagen D, et al.
Clin Exp Metastasis
. 2024 Dec;
42(1):1.
PMID: 39666203
The behaviour of metastases in patients with liver-metastatic colorectal cancer (CRC) is still not adequately considered during treatment planning. However, studies in large cohorts have shown that the disease course...
3.
Galema H, Neijenhuis L, Lauwerends L, Dekker-Ensink N, Verhoef C, Vahrmeijer A, et al.
Mol Imaging Biol
. 2024 Nov;
26(6):955-964.
PMID: 39562416
Purpose: Oesophaegal cancer patients with a clinical complete response (CR) after neoadjuvant chemoradiotherapy (nCRT) are candidates for an active surveillance strategy. Regrowth rates of 40% after initial clinical CR indicate...
4.
Kus Ozturk S, Bokhorst J, Baumann E, Sheahan K, van de Velde C, Marijnen C, et al.
Mod Pathol
. 2024 Nov;
38(2):100655.
PMID: 39522647
Owing to insufficient evidence, tumor budding (TB) is not currently evaluated in colorectal cancer (CRC) biopsies. This study investigates TB in CRC by establishing the value of intratumoral budding (ITB)...
5.
Hoppener D, Aswolinskiy W, Qian Z, Tellez D, Nierop P, Starmans M, et al.
BJS Open
. 2024 Oct;
8(6).
PMID: 39471410
Background: Histopathological growth patterns are one of the strongest prognostic factors in patients with resected colorectal liver metastases. Development of an efficient, objective and ideally automated histopathological growth pattern scoring...
6.
Farshadi E, Wang W, Mohammad F, van der Oost E, Doukas M, van Eijck C, et al.
Sci Rep
. 2024 Oct;
14(1):25468.
PMID: 39462012
Pancreatic ductal adenocarcinoma (PDAC) presents challenges in detecting somatic mutations due to its complex cellular composition. This study investigated the utility of patient-derived organoids (PDOs) to overcome these obstacles and...
7.
Heredia M, Charrout M, Klomberg R, Aardoom M, Jongsma M, Kemos P, et al.
Mucosal Immunol
. 2024 Sep;
18(1):76-89.
PMID: 39332767
Inflammatory bowel disease (IBD) chronicity results from memory T helper cell (Tmem) reactivation. Identifying patient-specific immunotypes is crucial for tailored treatment. We conducted a comprehensive study integrating circulating immune proteins...
8.
Suurmeijer J, Wismans L, Hendriks T, Bruynzeel A, Nuyttens J, Intven M, et al.
BMJ Open
. 2024 Sep;
14(9):e087193.
PMID: 39317507
Introduction: Postoperative pancreatic fistula (POPF) occurs in 25% of patients undergoing a high-risk pancreatoduodenectomy (PD) and is a driving cause of major morbidity, mortality, prolonged hospital stay and increased costs...
9.
van t Land F, Willemsen M, Bezemer K, van der Burg S, van den Bosch T, Doukas M, et al.
J Clin Oncol
. 2024 Jul;
42(26):3083-3093.
PMID: 38950309
Purpose: Immunotherapies have shown limited responses in patients with advanced pancreatic cancer. Recently, we reported that dendritic cell (DC)-based immunotherapy induced T-cell responses against pancreatic cancer antigens. The primary objective...
10.
Verhagen M, Joosten R, Schmitt M, Valimaki N, Sacchetti A, Rajamaki K, et al.
Nat Genet
. 2024 Jun;
56(7):1456-1467.
PMID: 38902475
According to conventional views, colon cancer originates from stem cells. However, inflammation, a key risk factor for colon cancer, has been shown to suppress intestinal stemness. Here, we used Paneth...