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Michaela Schneiderova

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Articles 21
Citations 459
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Recent Articles
1.
Sojka L, Opattova A, Bartu L, Horak J, Korenkova V, Novosadova V, et al.
Oncol Lett . 2023 Jan; 25(2):72. PMID: 36688110
MUC13, a transmembrane mucin glycoprotein, is overexpressed in colorectal cancer (CRC), however, its regulation and functions are not fully understood. It has been shown that MUC13 protects colonic epithelial cells...
2.
Horak J, Dolnikova A, Cumaogullari O, Cumova A, Navvabi N, Vodickova L, et al.
Front Oncol . 2022 Nov; 12:959407. PMID: 36324569
Cancer therapy failure is a fundamental challenge in cancer treatment. One of the most common reasons for therapy failure is the development of acquired resistance of cancer cells. DNA-damaging agents...
3.
Kavec M, Urbanova M, Makovicky P, Opattova A, Tomasova K, Kroupa M, et al.
Int J Mol Sci . 2022 May; 23(10). PMID: 35628513
Oxidative stress, oxidative DNA damage and resulting mutations play a role in colorectal carcinogenesis. Impaired equilibrium between DNA damage formation, antioxidant status, and DNA repair capacity is responsible for the...
4.
Vodenkova S, Kroupa M, Polivkova Z, Musak L, Ambrus M, Schneiderova M, et al.
Oncol Rep . 2020 Oct; 44(5):2219-2230. PMID: 33000239
Accumulation of non‑specific structural chromosomal aberrations (CAs) and telomere shortening contribute to genome instability, which constitutes as one of the hallmarks of cancer. CAs arise due to direct DNA damage...
5.
Vodicka P, Urbanova M, Makovicky P, Tomasova K, Kroupa M, Stetina R, et al.
Int J Mol Sci . 2020 Apr; 21(7). PMID: 32252452
Oxidative stress with subsequent premutagenic oxidative DNA damage has been implicated in colorectal carcinogenesis. The repair of oxidative DNA damage is initiated by lesion-specific DNA glycosylases (hOGG1, NTH1, MUTYH). The...
6.
Burocziova M, Burdova K, Martinikova A, Kasparek P, Kleiblova P, Danielsen S, et al.
Cell Death Dis . 2019 Oct; 10(11):818. PMID: 31659152
Protein phosphatase magnesium-dependent 1 delta (PPM1D) terminates cell response to genotoxic stress by negatively regulating the tumor suppressor p53 and other targets at chromatin. Mutations in the exon 6 of...
7.
Kleiblova P, Stolarova L, Krizova K, Lhota F, Hojny J, Zemankova P, et al.
Klin Onkol . 2019 Aug; 32(Supplementum2):36-50. PMID: 31409080
Background: Hereditary mutations in the CHEK2 gene (which encodes CHK2 kinase) contribute to a moderately increased risk of breast cancer (BC) and other cancers. Large variations in the frequency of...
8.
Kunzmann A, Proenca M, Jordao H, Jiraskova K, Schneiderova M, Levy M, et al.
Eur J Clin Microbiol Infect Dis . 2019 Aug; 38(10):1891-1899. PMID: 31367996
There is increasing evidence indicating a role for Fusobacterium nucleatum (F. nucleatum) in colorectal cancer (CRC) development and prognosis. This study evaluated F. nucleatum as a prognostic biomarker, by assessing...
9.
Kroupa M, Rachakonda S, Liska V, Srinivas N, Urbanova M, Jiraskova K, et al.
Br J Cancer . 2019 Jul; 121(4):344-350. PMID: 31312029
Background: Telomeres, repetitive DNA capping ends of eukaryotic chromosomes, are important in the maintenance of genomic integrity. Perturbed telomeres are common features of many human malignancies, including colorectal cancer. Methods:...
10.
Kleiblova P, Stolarova L, Krizova K, Lhota F, Hojny J, Zemankova P, et al.
Int J Cancer . 2019 May; 145(7):1782-1797. PMID: 31050813
Germline mutations in checkpoint kinase 2 (CHEK2), a multiple cancer-predisposing gene, increase breast cancer (BC) risk; however, risk estimates differ substantially in published studies. We analyzed germline CHEK2 variants in...