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Michaela Schedel

Explore the profile of Michaela Schedel including associated specialties, affiliations and a list of published articles. Areas
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Articles 30
Citations 560
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Recent Articles
1.
Gonzalez-Rubio J, Kubiza H, Xu Y, Koenigs-Werner H, Schmitz M, Schedel M, et al.
Adv Sci (Weinh) . 2025 Jan; :e2408131. PMID: 39887579
Pericytes are a key player in vascularization, protecting endothelial cells from external harm and promoting the formation of new vessels when necessary. However, pericytic identity and its relationship with other...
2.
Barbet K, Schmitz M, Westholter D, Kamler M, Rutten S, Thiebes A, et al.
Respir Res . 2024 Dec; 25(1):439. PMID: 39719562
Background: Using primary airway epithelial cells (AEC) is essential to mimic more closely different types and stages of lung disease in humans while reducing or even replacing animal experiments. Access...
3.
Gonzalez-Rubio J, Zeevaert K, Buhl E, Schedel M, Jockenhoevel S, Cornelissen C, et al.
Life Sci . 2024 Dec; 361:123298. PMID: 39647809
Aims: Mesenchymal stromal cells (MSCs) are being tested and accepted as a source for cell therapy worldwide. However, the advanced age of the patients, together with the difficulties in achieving...
4.
Jurgens M, Claus M, Wingert S, Alexander Niemann J, Picard L, Hennes E, et al.
Eur J Immunol . 2024 Oct; 54(12):e2451299. PMID: 39350450
Adrenergic receptors (ARs) are preferentially expressed by innate lymphocytes such as natural killer (NK) cells. Here, we study the effect of epinephrine-mediated stimulation of the β2-adrenergic receptor (β2AR) on the...
5.
Wang M, Schedel M, Gelfand E
J Allergy Clin Immunol . 2024 Mar; 154(1):51-58. PMID: 38555980
Gene editing technology has emerged as a powerful tool in all aspects of health research and continues to advance our understanding of critical and essential elements in disease pathophysiology. The...
6.
Schedel M, Leach S, Strand M, Danhorn T, Macbeth M, Faino A, et al.
Allergy . 2022 Aug; 78(1):244-257. PMID: 35993851
Background: The prevalence of atopic diseases has increased with atopic dermatitis (AD) as the earliest manifestation. We assessed if molecular risk factors in atopic mothers influence their infants' susceptibility to...
7.
Hu G, Hauk P, Zhang N, Elsegeiny W, Guardia C, Kullas A, et al.
Autophagy . 2022 Jul; 19(2):678-691. PMID: 35838483
BCL2: BCL2 apoptosis regulator; BCL10: BCL10 immune signaling adaptor; CARD11: caspase recruitment domain family member 11; CBM: CARD11-BCL10-MALT1; CR2: complement C3d receptor 2; EBNA: Epstein Barr nuclear antigen; EBV: Epstein-Barr...
8.
Laubhahn K, Bock A, Zeber K, Unterschemmann S, Kunze S, Schedel M, et al.
Pediatr Allergy Immunol . 2021 Dec; 33(2):e13721. PMID: 34919286
Background: Childhood wheeze represents a first symptom of asthma. Early identification of children at risk for wheeze related to 17q12-21 variants and their underlying immunological mechanisms remain unknown. We aimed...
9.
Macbeth M, Joetham A, Gelfand E, Schedel M
Int J Mol Sci . 2021 Apr; 22(9). PMID: 33925531
The impact of naturally occurring regulatory T cells (nTregs) on the suppression or induction of lung allergic responses in mice depends on the nuclear environment and the production of the...
10.
Joetham A, Schedel M, Ning F, Wang M, Takeda K, Gelfand E
J Allergy Clin Immunol . 2019 Oct; 145(3):933-946.e4. PMID: 31626843
Background: Inducible CD4CD25 regulatory T (iTreg) cells can become pathogenic effector cells, enhancing lung allergic responses. Objective: We aimed to define the underlying cellular and molecular pathways activated by TGF-β,...