Michael Weitnauer
Overview
Explore the profile of Michael Weitnauer including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
410
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0
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Recent Articles
1.
Sultan C, Weitnauer M, Turinsky M, Kessler T, Brune M, Gleissner C, et al.
Cardiovasc Res
. 2019 Aug;
116(6):1214-1225.
PMID: 31373353
Aims: Endothelial dysfunction is a major contributor to the pathogenesis of atherosclerosis. CD40-CD40 ligand interactions confer a pro-inflammatory phenotype to endothelial cells (ECs). Recently, a thymine to cytosine transition (-1T>C)...
2.
Zhang Z, Trautz B, Kracun D, Vogel F, Weitnauer M, Hochkogler K, et al.
Antioxid Redox Signal
. 2018 Jul;
30(1):56-73.
PMID: 30044141
Aims: Hypoxia and reactive oxygen species (ROS) have been shown to play a role in the pathogenesis of pulmonary hypertension (PH), a potentially fatal disorder characterized by pulmonary vascular remodeling,...
3.
Boutin S, Weitnauer M, Hassel S, Graeber S, Stahl M, Dittrich A, et al.
J Cyst Fibros
. 2018 Jan;
17(3):348-355.
PMID: 29336943
Background: Chronic airway infection with Pseudomonas aeruginosa is a major risk factor of progression of lung disease in patients with cystic fibrosis (CF). Chronic P. aeruginosa infection evolves from intermittent...
4.
Ng Kuet Leong N, Brombacher F, Dalpke A, Weitnauer M
Immunobiology
. 2017 Feb;
222(5):759-767.
PMID: 28209270
Airway epithelial cells induce a tolerogenic microenvironment by modulating immune cells in the lung. We recently showed that the supernatant of airway epithelial cells induces two marker genes of alternative...
5.
Zimmer J, Weitnauer M, Boutin S, Kublbeck G, Thiele S, Walker P, et al.
Front Immunol
. 2016 Dec;
7:514.
PMID: 27917175
Suppressor of cytokine signaling 1 (SOCS1) is a negative feedback inhibitor of cytoplasmic Janus kinase and signal transducer and activator of transcription (STAT) signaling. SOCS1 also contains a nuclear localization...
6.
Mijosek V, Lasitschka F, Warth A, Zabeck H, Dalpke A, Weitnauer M
J Innate Immun
. 2016 Jul;
8(5):464-78.
PMID: 27423489
Endoplasmic reticulum (ER) stress is associated with chronic pulmonary inflammatory diseases. We hypothesized that the combined activation of both Toll-like receptor (TLR) signaling and ER stress might increase inflammatory reactions...
7.
Oumouna M, Weitnauer M, Mijosek V, Schmidt L, Eigenbrod T, Dalpke A
Immunobiology
. 2015 Jul;
220(11):1240-5.
PMID: 26153873
Airway epithelial cells (AEC) are the first line of defense against airborne infectious microbes and play an important role in regulating the local immune response. However, the interplay of epithelial...
8.
Bertram K, Valcu C, Weitnauer M, Linne U, Gorlach A
PLoS One
. 2015 Mar;
10(3):e0122002.
PMID: 25806803
NADPH oxidases are important sources of reactive oxygen species (ROS) which act as signaling molecules in the regulation of protein expression, cell proliferation, differentiation, migration and cell death. The NOX1...
9.
Boutin S, Graeber S, Weitnauer M, Panitz J, Stahl M, Clausznitzer D, et al.
PLoS One
. 2015 Jan;
10(1):e0116029.
PMID: 25629612
Changes in the airway microbiome may be important in the pathophysiology of chronic lung disease in patients with cystic fibrosis. However, little is known about the microbiome in early cystic...
10.
Weitnauer M, Schmidt L, Ng Kuet Leong N, Muenchau S, Lasitschka F, Eckstein V, et al.
J Immunol
. 2014 Jun;
193(3):1475-84.
PMID: 24965772
Airway epithelial cells mount a tolerogenic microenvironment that reduces the proinflammatory potential of respiratory dendritic cells (DCs). We recently demonstrated that tracheal epithelial cells continuously secrete soluble mediators that affect...