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Michael W Marcus

Explore the profile of Michael W Marcus including associated specialties, affiliations and a list of published articles. Areas
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Articles 38
Citations 1185
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Recent Articles
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Ji X, Mukherjee S, Landi M, Bosse Y, Joubert P, Zhu D, et al.
Nat Commun . 2020 May; 11(1):2220. PMID: 32393777
Few germline mutations are known to affect lung cancer risk. We performed analyses of rare variants from 39,146 individuals of European ancestry and investigated gene expression levels in 7,773 samples....
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Acha-Sagredo A, Uko B, Pantazi P, Bediaga N, Moschandrea C, Rainbow L, et al.
Br J Cancer . 2020 Feb; 122(7):1050-1058. PMID: 32020063
Background: Long non-coding RNAs compose an important level of epigenetic regulation in normal physiology and disease. Despite the plethora of publications of lncRNAs in human cancer, the landscape is still...
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Ghimire B, Maroni R, Vulkan D, Shah Z, Gaynor E, Timoney M, et al.
Lung Cancer . 2019 Jul; 134:66-71. PMID: 31319997
Objectives: This Liverpool Healthy Lung Programme is a response to high rates of lung cancer and respiratory diseases locally and aims to diagnose lung cancer at an earlier stage by...
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Spanopoulos D, Busse M, Webb J, Tebboth A, Gollop N, Marcus M
Clin Ther . 2019 Jun; 41(8):1622-1630. PMID: 31164243
Recently, 2 dipeptidyl peptidase-4 (DPP-4) inhibitors, sitagliptin and saxagliptin, adjusted dosing specification from creatinine clearance to glomerular filtration rate, more typically reported in routine laboratory tests. This cross-sectional study examines...
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Marcus M, Duffy S, Devaraj A, Green B, Oudkerk M, Baldwin D, et al.
Thorax . 2019 Apr; 74(8):761-767. PMID: 31028232
Background: Estimation of the clinical probability of malignancy in patients with pulmonary nodules will facilitate early diagnosis, determine optimum patient management strategies and reduce overall costs. Methods: Data from the...
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Li Y, Xiao X, Bosse Y, Gorlova O, Gorlov I, Han Y, et al.
Oncotarget . 2019 Apr; 10(19):1760-1774. PMID: 30956756
The development of cancer is driven by the accumulation of many oncogenesis-related genetic alterations and tumorigenesis is triggered by complex networks of involved genes rather than independent actions. To explore...
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Zhu Y, Wei Y, Zhang R, Dong X, Shen S, Zhao Y, et al.
Cancer Epidemiol Biomarkers Prev . 2019 Feb; 28(5):935-942. PMID: 30700444
Background: Platelets are a critical element in coagulation and inflammation, and activated platelets are linked to cancer risk through diverse mechanisms. However, a causal relationship between platelets and risk of...
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Ji X, Bosse Y, Landi M, Gui J, Xiao X, Qian D, et al.
Nat Commun . 2018 Aug; 9(1):3221. PMID: 30104567
Genome-wide association studies (GWAS) identified the chromosome 15q25.1 locus as a leading susceptibility region for lung cancer. However, the pathogenic pathways, through which susceptibility SNPs within chromosome 15q25.1 affects lung...