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Michael W Chiu

Explore the profile of Michael W Chiu including associated specialties, affiliations and a list of published articles. Areas
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Articles 3
Citations 171
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Recent Articles
1.
Rizzi A, Murkli S, McNeill J, Yao W, Sullivan M, Gilson M, et al.
J Comput Aided Mol Des . 2018 Nov; 32(10):937-963. PMID: 30415285
Accurately predicting the binding affinities of small organic molecules to biological macromolecules can greatly accelerate drug discovery by reducing the number of compounds that must be synthesized to realize desired...
2.
Lemaire C, Liu S, Wilkerson C, Ramani V, Barzanian N, Huang K, et al.
SLAS Technol . 2018 Jan; 23(1):16-29. PMID: 29355087
Tumor tissue biopsies are invasive, costly, and collect a limited cell population not completely reflective of patient cancer cell diversity. Circulating tumor cells (CTCs) can be isolated from a simple...
3.
Yin J, Henriksen N, Slochower D, Shirts M, Chiu M, Mobley D, et al.
J Comput Aided Mol Des . 2016 Sep; 31(1):1-19. PMID: 27658802
The ability to computationally predict protein-small molecule binding affinities with high accuracy would accelerate drug discovery and reduce its cost by eliminating rounds of trial-and-error synthesis and experimental evaluation of...