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Michael Uhl

Explore the profile of Michael Uhl including associated specialties, affiliations and a list of published articles. Areas
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Articles 26
Citations 526
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Recent Articles
1.
Favretto D, Cooper G, Andraus M, Sporkert F, Agius R, Appenzeller B, et al.
Drug Test Anal . 2023 Jun; 15(9):1042-1046. PMID: 37332075
No abstract available.
2.
Uhl M, Rabsch D, Eggenhofer F, Backofen R
Bioinformatics . 2021 Nov; 38(4):1139-1140. PMID: 34734974
Motivation: CLIP-seq is by far the most widely used method to determine transcriptome-wide binding sites of RNA-binding proteins (RBPs). The binding site locations are identified from CLIP-seq read data by...
3.
Uhl M, Tran V, Heyl F, Backofen R
Gigascience . 2021 Aug; 10(8). PMID: 34406415
Background: Cross-linking and immunoprecipitation followed by next-generation sequencing (CLIP-seq) is the state-of-the-art technique used to experimentally determine transcriptome-wide binding sites of RNA-binding proteins (RBPs). However, it relies on gene expression,...
4.
Davis J, Guertin F, Guidry T, Rogers M, Saunders Z, Uhl M
Integr Environ Assess Manag . 2021 Apr; 18(1):74-81. PMID: 33915028
Companies are increasingly focused on driving the adoption of nature-based solutions across their organizations. Yet, implementing nature-based solutions within existing regulatory frameworks poses a unique set of challenges. In this...
5.
Uhl M, Tran V, Backofen R
BMC Genomics . 2020 Dec; 21(1):894. PMID: 33334306
Background: Current peak callers for identifying RNA-binding protein (RBP) binding sites from CLIP-seq data take into account genomic read profiles, but they ignore the underlying transcript information, that is information...
6.
Uhl M, Lindenmann A, Matthiesen S
Appl Ergon . 2020 Dec; 92:103338. PMID: 33310294
In order to be able to develop a hammer drill with which the user can work as ergonomically and productively as possible, the relevant influencing factors must be known. In...
7.
Heyl F, Maticzka D, Uhl M, Backofen R
Gigascience . 2020 Nov; 9(11). PMID: 33179042
Background: Post-transcriptional regulation via RNA-binding proteins plays a fundamental role in every organism, but the regulatory mechanisms lack important understanding. Nevertheless, they can be elucidated by cross-linking immunoprecipitation in combination...
8.
Raden M, Gutmann F, Uhl M, Backofen R
Int J Mol Sci . 2020 Jun; 21(11). PMID: 32481751
In silico RNA-RNA interaction prediction is widely applied to identify putative interaction partners and to assess interaction details in base pair resolution. To verify specific interactions, in vitro evidence can...
9.
Zhang Y, Pitchiaya S, Cieslik M, Niknafs Y, Tien J, Hosono Y, et al.
Nat Genet . 2018 May; 50(6):814-824. PMID: 29808028
The androgen receptor (AR) plays a critical role in the development of the normal prostate as well as prostate cancer. Using an integrative transcriptomic analysis of prostate cancer cell lines...
10.
Franz T, Scheufler F, Stein K, Uhl M, Dame T, Schwarz G, et al.
Forensic Sci Int . 2018 May; 288:223-226. PMID: 29775923
Drugs which are commonly smoked or sniffed (e.g. cocaine), can contaminate hair through smoke or dust; therefore testing for metabolites, especially hydroxy metabolites, is highly recommended. The presence of hydroxy...