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Michael Tranfaglia

Explore the profile of Michael Tranfaglia including associated specialties, affiliations and a list of published articles. Areas
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Citations 496
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Recent Articles
1.
Cogram P, Alkon D, Crockford D, Deacon R, Hurley M, Altimiras F, et al.
Sci Rep . 2020 Oct; 10(1):18058. PMID: 33093534
Fragile X syndrome (FXS), an X-chromosome linked intellectual disability, is the leading monogenetic cause of autism spectrum disorder (ASD), a neurodevelopmental condition that currently has no specific drug treatment. Building...
2.
Gurney M, Cogram P, Deacon R, Rex C, Tranfaglia M
Sci Rep . 2017 Nov; 7(1):14653. PMID: 29116166
Fragile-X syndrome (FXS) patients display intellectual disability and autism spectrum disorder due to silencing of the X-linked, fragile-X mental retardation-1 (FMR1) gene. Dysregulation of cAMP metabolism is a consistent finding...
3.
Westmark C, Westmark P, ORiordan K, Ray B, Hervey C, Salamat M, et al.
PLoS One . 2011 Nov; 6(10):e26549. PMID: 22046307
Fragile X syndrome (FXS) is the most common form of inherited intellectual disability and the leading known genetic cause of autism. Fragile X mental retardation protein (FMRP), which is absent...
4.
Paribello C, Tao L, Folino A, Berry-Kravis E, Tranfaglia M, Ethell I, et al.
BMC Neurol . 2010 Oct; 10:91. PMID: 20937127
Background: Fragile X syndrome (FXS) is a disorder characterized by a variety of disabilities, including cognitive deficits, attention-deficit/hyperactivity disorder, autism, and other socio-emotional problems. It is hypothesized that the absence...
5.
Hagerman R, Berry-Kravis E, Kaufmann W, Ono M, Tartaglia N, Lachiewicz A, et al.
Pediatrics . 2009 Jan; 123(1):378-90. PMID: 19117905
The FMR1 mutations can cause a variety of disabilities, including cognitive deficits, attention-deficit/hyperactivity disorder, autism, and other socioemotional problems, in individuals with the full mutation form (fragile X syndrome) and...