Michael Schorpp
Overview
Explore the profile of Michael Schorpp including associated specialties, affiliations and a list of published articles.
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Articles
37
Citations
887
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Recent Articles
1.
Lawir D, Soza-Ried C, Iwanami N, Siamishi I, Bylund G, O Meara C, et al.
Commun Biol
. 2024 Feb;
7(1):247.
PMID: 38424361
No abstract available.
2.
OMeara C, Guerri L, Lawir D, Mateos F, Iconomou M, Iwanami N, et al.
Commun Biol
. 2024 Feb;
7(1):182.
PMID: 38355822
No abstract available.
3.
Lawir D, Soza-Ried C, Iwanami N, Siamishi I, Bylund G, O Meara C, et al.
Commun Biol
. 2024 Jan;
7(1):31.
PMID: 38182651
The stability of cellular phenotypes in developing organisms depends on error-free transmission of epigenetic and genetic information during mitosis. Methylation of cytosine residues in genomic DNA is a key epigenetic...
4.
Schorpp M, Swann J, Hess I, Ho H, Pietsch T, Boehm T
Eur J Immunol
. 2023 Sep;
53(12):e2350725.
PMID: 37724048
In mammals, T-cell development depends on the activity of the Foxn1 transcription factor in the thymic epithelium; mutations in the vertebrate-specific Foxn1 gene are associated with profound T-cell lymphopenia and...
5.
Swann J, Grammer C, Schorpp M, Boehm T
BMC Immunol
. 2023 Jul;
24(1):20.
PMID: 37480016
Background: The anglerfish, belonging to the teleost order Lophiiformes, are a diverse and species-rich group of fish that are known to exhibit a number of unique morphological, reproductive and immunological...
6.
Giorgetti O, OMeara C, Schorpp M, Boehm T
Nature
. 2023 Jun;
619(7968):193-200.
PMID: 37344590
Lymphocytes of vertebrate adaptive immune systems acquired the capability to assemble, from split genes in the germline, billions of functional antigen receptors. These receptors show specificity; unlike the broadly tuned...
7.
Hess I, Sagar , O Meara C, Grun D, Schorpp M, Boehm T
Sci Rep
. 2022 Dec;
12(1):21401.
PMID: 36496511
The zinc finger transcription factor Ikaros1 (Ikzf1) is required for lymphoid development in mammals. Four zinc fingers constitute its DNA binding domain and two zinc fingers are present in the...
8.
OMeara C, Guerri L, Lawir D, Mateos F, Iconomou M, Iwanami N, et al.
Commun Biol
. 2021 Oct;
4(1):1201.
PMID: 34671088
To capture the global gene network regulating the differentiation of immature T cells in an unbiased manner, large-scale forward genetic screens in zebrafish were conducted and combined with genetic interaction...
9.
Morimoto R, Swann J, Nusser A, Trancoso I, Schorpp M, Boehm T
Open Biol
. 2021 Feb;
11(2):200383.
PMID: 33622100
In vertebrates, the development of lymphocytes from undifferentiated haematopoietic precursors takes place in so-called primary lymphoid organs, such as the thymus. Therein, lymphocytes undergo a complex differentiation and selection process...
10.
Giorgetti O, Shingate P, OMeara C, Ravi V, Pillai N, Tay B, et al.
Sci Adv
. 2021 Feb;
7(1).
PMID: 33523858
The rules underlying the structure of antigen receptor repertoires are not yet fully defined, despite their enormous importance for the understanding of adaptive immunity. With current technology, the large antigen...