Michael S Minett
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Explore the profile of Michael S Minett including associated specialties, affiliations and a list of published articles.
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15
Citations
849
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Recent Articles
1.
Minett M, Eijkelkamp N, Wood J
PLoS One
. 2021 Jan;
16(1):e0245813.
PMID: 33449972
[This corrects the article DOI: 10.1371/journal.pone.0104458.].
2.
Koppers M, Cagnetta R, Shigeoka T, Wunderlich L, Vallejo-Ramirez P, Lin J, et al.
Elife
. 2019 Nov;
8.
PMID: 31746735
Extrinsic cues trigger the local translation of specific mRNAs in growing axons via cell surface receptors. The coupling of ribosomes to receptors has been proposed as a mechanism linking signals...
3.
Brain-derived neurotrophic factor derived from sensory neurons plays a critical role in chronic pain
Sikandar S, Minett M, Millet Q, Santana-Varela S, Lau J, Wood J, et al.
Brain
. 2018 Feb;
141(4):1028-1039.
PMID: 29394316
Many studies support the pro-nociceptive role of brain-derived neurotrophin factor (BDNF) in pain processes in the peripheral and central nervous system. We have previously shown that nociceptor-derived BDNF is involved...
4.
Habib A, Matsuyama A, Okorokov A, Santana-Varela S, Bras J, Aloisi A, et al.
Brain
. 2017 Dec;
141(2):365-376.
PMID: 29253101
Chronic pain is a major global public health issue causing a severe impact on both the quality of life for sufferers and the wider economy. Despite the significant clinical burden,...
5.
Deuis J, Dekan Z, Wingerd J, Smith J, Munasinghe N, Bhola R, et al.
Sci Rep
. 2017 May;
7:46816.
PMID: 28548111
No abstract available.
6.
Deuis J, Dekan Z, Wingerd J, Smith J, Munasinghe N, Bhola R, et al.
Sci Rep
. 2017 Jan;
7:40883.
PMID: 28106092
Human genetic studies have implicated the voltage-gated sodium channel Na1.7 as a therapeutic target for the treatment of pain. A novel peptide, μ-theraphotoxin-Pn3a, isolated from venom of the tarantula Pamphobeteus...
7.
Minett M, Pereira V, Sikandar S, Matsuyama A, Lolignier S, Kanellopoulos A, et al.
Nat Commun
. 2015 Dec;
6:8967.
PMID: 26634308
Loss-of-function mutations in the SCN9A gene encoding voltage-gated sodium channel Nav1.7 cause congenital insensitivity to pain in humans and mice. Surprisingly, many potent selective antagonists of Nav1.7 are weak analgesics....
8.
Minett M, Quick K, Wood J
Curr Protoc Mouse Biol
. 2015 Jun;
1(3):383-412.
PMID: 26068997
Pain afflicts a fifth of the population, and animal models have proven useful in target validation and analgesic drug development. Thresholds to pain are tested by applying a sensory stimulus,...
9.
Werdehausen R, Mittnacht S, Bee L, Minett M, Armbruster A, Bauer I, et al.
Pain
. 2015 May;
156(9):1647-1659.
PMID: 25932687
Glycine transporter 1 (GlyT1) plays a crucial role in regulating extracellular glycine concentrations and might thereby constitute a new drug target for the modulation of glycinergic inhibition in pain signaling....
10.
Minett M, Eijkelkamp N, Wood J
PLoS One
. 2014 Aug;
9(8):e104458.
PMID: 25101983
Transgenic mouse behavioural analysis has furthered our understanding of the molecular and cellular mechanisms underlying damage sensing and pain. However, it is not unusual for conflicting data on the pain...