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Michael S Kobor

Explore the profile of Michael S Kobor including associated specialties, affiliations and a list of published articles. Areas
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Articles 253
Citations 9429
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Recent Articles
11.
Zhuang B, Jude M, Konwar C, Yusupov N, Ryan C, Engelbrecht H, et al.
bioRxiv . 2024 Jul; PMID: 39005299
Background: The recently launched DNA methylation profiling platform, Illumina MethylationEPIC BeadChip Infinium microarray v2.0 (EPICv2), is highly correlated with measurements obtained from its predecessor MethylationEPIC BeadChip Infinium microarray v1.0 (EPICv1)....
12.
Hernandez Cordero A, Li X, Yang J, Xi Yang C, Shaipanich T, MacIsaac J, et al.
Biomedicines . 2024 Jun; 12(6). PMID: 38927468
Background: DNA methylation may be a link between HIV, aging, and the increased risk of lung comorbidities. We investigated whether bronchoalveolar lavage (BAL) cells of people living with HIV (PLWH)...
13.
Salama O, Hizon N, Del Vecchio M, Kolsun K, Fonseca M, Lin D, et al.
Clin Epigenetics . 2024 May; 16(1):65. PMID: 38741114
Objective: Youth-onset type 2 diabetes (T2D) is physiologically distinct from adult-onset, but it is not clear how the two diseases differ at a molecular level. In utero exposure to maternal...
14.
Marchi E, Hinks T, Richardson M, Khalfaoui L, Symon F, Rajasekar P, et al.
Allergy . 2024 Apr; 79(7):1831-1843. PMID: 38686450
Background: The effects of inhaled corticosteroids (ICS) on healthy airways are poorly defined. Objectives: To delineate the effects of ICS on gene expression in healthy airways, without confounding caused by...
15.
Pett L, Li Z, Abrishamcar S, Hodge K, Everson T, Christensen G, et al.
Aging (Albany NY) . 2024 Apr; 16(8):6694-6716. PMID: 38663907
Previous research has found that living in a disadvantaged neighborhood is associated with poor health outcomes. Living in disadvantaged neighborhoods may alter inflammation and immune response in the body, which...
16.
Hernandez Cordero A, Li X, Xi Yang C, Ambalavanan A, MacIsaac J, Kobor M, et al.
Eur Respir J . 2024 Apr; 63(5). PMID: 38609099
No abstract available.
17.
Ryan C, Lee N, Carba D, MacIsaac J, Lin D, Atashzay P, et al.
Proc Natl Acad Sci U S A . 2024 Apr; 121(16):e2317290121. PMID: 38588424
A central prediction of evolutionary theory is that energy invested into reproduction comes at the expense of somatic maintenance and repair, accelerating biological aging. Supporting this prediction are findings that...
18.
Lee S, Sbihi H, MacIsaac J, Balshaw R, Ambalavanan A, Subbarao P, et al.
Environ Health Perspect . 2024 Apr; 132(4):47004. PMID: 38573328
Background: Evidence suggests that prenatal air pollution exposure alters DNA methylation (DNAm), which could go on to affect long-term health. It remains unclear whether DNAm alterations present at birth persist...
19.
Hastings W, Ye Q, Wolf S, Ryan C, Das S, Huffman K, et al.
Aging Cell . 2024 Mar; 23(6):e14149. PMID: 38504468
Caloric restriction (CR) modifies lifespan and aging biology in animal models. The Comprehensive Assessment of Long-Term Effects of Reducing Intake of Energy (CALERIE™) 2 trial tested translation of these findings...
20.
Eisenberg D, Ryan C, Lee N, Carba D, MacIsaac J, Dever K, et al.
Geroscience . 2024 Mar; 46(4):3957-3969. PMID: 38466455
In humans, DNA methylation (DNAm) based estimators of telomere length (TL) have been shown to better predict TL-associated variables (e.g., age, sex, and mortality) than TL itself. The biological significance...