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Michael Rape

Explore the profile of Michael Rape including associated specialties, affiliations and a list of published articles. Areas
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Articles 92
Citations 7733
Followers 0
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Recent Articles
1.
Freeberg A, Rape M
Nature . 2025 Jan; 638(8050):330-332. PMID: 39881173
No abstract available.
2.
Liu S, Tan C, Melo-Gavin C, Ginzberg M, Blutrich R, Patel N, et al.
Elife . 2025 Jan; 14. PMID: 39791360
Proliferating animal cells maintain a stable size distribution over generations despite fluctuations in cell growth and division size. Previously, we showed that cell size control involves both cell size checkpoints,...
3.
Ingersoll A, McCloud D, Hu J, Rape M
bioRxiv . 2024 Dec; PMID: 39651249
The oxidative stress response is centered on the transcription factor NRF2 and protects cells from reactive oxygen species (ROS). While ROS inhibit the E3 ligase CUL3 to stabilize NRF2 and...
4.
McMinimy R, Manford A, Gee C, Chandrasekhar S, Mousa G, Chuang J, et al.
Mol Cell . 2024 Dec; 84(23):4612-4628.e13. PMID: 39642856
While reactive oxygen species (ROS) have long been known to drive aging and neurodegeneration, their persistent depletion below basal levels also disrupts organismal function. Cells counteract loss of basal ROS...
5.
Haakonsen D, Heider M, Ingersoll A, Vodehnal K, Witus S, Uenaka T, et al.
Nature . 2024 Jan; 626(8000):874-880. PMID: 38297121
Stress response pathways detect and alleviate adverse conditions to safeguard cell and tissue homeostasis, yet their prolonged activation induces apoptosis and disrupts organismal health. How stress responses are turned off...
6.
Mark K, Kolla S, Aguirre J, Garshott D, Schmitt S, Haakonsen D, et al.
Cell . 2023 Sep; 186(19):4252-4253. PMID: 37714136
No abstract available.
7.
Henning N, Manford A, Spradlin J, Brittain S, Zhang E, McKenna J, et al.
J Am Chem Soc . 2023 Sep; 145(38):21142. PMID: 37708357
No abstract available.
8.
Mark K, Kolla S, Aguirre J, Garshott D, Schmitt S, Haakonsen D, et al.
Cell . 2023 Jul; 186(16):3460-3475.e23. PMID: 37478862
All eukaryotes require intricate protein networks to translate developmental signals into accurate cell fate decisions. Mutations that disturb interactions between network components often result in disease, but how the composition...
9.
Pandey N, Franklin K, Haynes K, Rape M, Cristea I
Trends Biochem Sci . 2023 Apr; 48(5):407-409. PMID: 37059055
No abstract available.
10.
Perier C, Nasinghe E, Charles I, Ssetaba L, Ahyong V, Bangs D, et al.
Glob Health Action . 2022 Jun; 15(1):2062175. PMID: 35730550
Science education and research have the potential to drive profound change in low- and middle-income countries (LMICs) through encouraging innovation, attracting industry, and creating job opportunities. However, in LMICs, research...