Michael R Hollingdale
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Explore the profile of Michael R Hollingdale including associated specialties, affiliations and a list of published articles.
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Articles
33
Citations
549
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Recent Articles
1.
Ganeshan H, Huang J, Belmonte M, Belmonte A, Inoue S, Velasco R, et al.
PLoS One
. 2025 Feb;
20(2):e0318098.
PMID: 39946433
Background: A three-antigen DNA-prime/chimpanzee adenovirus 63 (ChAd63) boost vaccine containing pre-erythrocytic Plasmodium falciparum (Pf) circumsporozoite protein (CSP), Pf apical membrane antigen-1 (AMA1) and malaria multiple epitopes (ME) fused to Pf...
2.
Sedegah M, Porter C, Goguet E, Ganeshan H, Belmonte M, Huang J, et al.
PLoS One
. 2022 Oct;
17(10):e0276241.
PMID: 36251675
Class I- and Class II-restricted epitopes have been identified across the SARS-CoV-2 structural proteome. Vaccine-induced and post-infection SARS-CoV-2 T-cell responses are associated with COVID-19 recovery and protection, but the precise...
3.
Sedegah M, Porter C, Hollingdale M, Ganeshan H, Huang J, Goforth C, et al.
PLoS One
. 2022 Apr;
17(4):e0266691.
PMID: 35390102
SARS-CoV-2 T cell responses are associated with COVID-19 recovery, and Class I- and Class II-restricted epitopes have been identified in the spike (S), nucleocapsid (N) and membrane (M) proteins and...
4.
Sklar M, Maiolatesi S, Patterson N, Sedegah M, Limbach K, Teneza-Mora N, et al.
PLoS One
. 2021 Sep;
16(9):e0256980.
PMID: 34495988
Background: A DNA-prime/human adenovirus serotype 5 (HuAd5) boost vaccine encoding Plasmodium falciparum (Pf) circumsporozoite protein (PfCSP) and Pf apical membrane antigen-1 (PfAMA1), elicited protection in 4/15 (27%) of subjects against...
5.
Sedegah M, Hollingdale M, Ganeshan H, Belmonte M, Huang J, Belmonte A, et al.
PLoS One
. 2021 Aug;
16(8):e0256396.
PMID: 34415964
Background: Immunization with radiation-attenuated sporozoites (RAS) by mosquito bites provides >90% sterile protection against Plasmodium falciparum malaria in humans. We conducted a clinical trial based on data from previous RAS...
6.
Hickey B, Teneza-Mora N, Lumsden J, Reyes S, Sedegah M, Garver L, et al.
PLoS One
. 2020 Jun;
15(6):e0233840.
PMID: 32555601
Background: Immunization with radiation-attenuated sporozoites (RAS) by mosquito bite provides >90% sterile protection against Plasmodium falciparum (Pf) malaria in humans. RAS invade hepatocytes but do not replicate. CD8+ T cells...
7.
Smith E, Limbach K, Rangel N, Oda K, Bolton J, Du M, et al.
PLoS One
. 2020 May;
15(5):e0232234.
PMID: 32407410
Only a small fraction of the antigens expressed by malaria parasites have been evaluated as vaccine candidates. A successful malaria subunit vaccine will likely require multiple antigenic targets to achieve...
8.
Limbach K, Stefaniak M, Chen P, Patterson N, Liao G, Weng S, et al.
Malar J
. 2017 Jul;
16(1):263.
PMID: 28673287
Background: A DNA-human Ad5 (HuAd5) prime-boost malaria vaccine has been shown to protect volunteers against a controlled human malaria infection. The potency of this vaccine, however, appeared to be affected...
9.
Sacci Jr J, Hollingdale M, Sedegah M
Pathog Dis
. 2017 May;
75(4).
PMID: 28475711
Plasmid DNA encoding Plasmodium yoelii circumsporozoite protein (PyCSP) followed by boosting with recombinant vaccinia virus containing the PyCSP elicited significant protective immunity in mice that was primarily mediated by CD8+...
10.
Sedegah M, Peters B, Hollingdale M, Ganeshan H, Huang J, Farooq F, et al.
PLoS One
. 2016 Dec;
11(12):e0168952.
PMID: 27997615
[This corrects the article DOI: 10.1371/journal.pone.0163026.].