Michael P Wajnrajch
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Explore the profile of Michael P Wajnrajch including associated specialties, affiliations and a list of published articles.
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35
Citations
283
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Recent Articles
1.
Maniatis A, Wajnrajch M, Thomas M, Chung S, Lee J
Ann Pediatr Endocrinol Metab
. 2025 Mar;
30(1):11-16.
PMID: 40049670
Growth hormone (GH) is crucial for childhood growth and body composition. In pediatric GH deficiency (pGHD), the pituitary gland fails to produce sufficient GH, which affects linear growth in childhood....
2.
Merchant N, Alvir J, Ericksen P, Loftus J, Cara J, Slade A, et al.
Orphanet J Rare Dis
. 2025 Feb;
20(1):90.
PMID: 40016839
Background: Achondroplasia, a disease characterized by disproportionate short stature and increased morbidity, affects daily function and quality of life over the lifetime of the individual. However, data are limited on...
3.
Nayak S, Wajnrajch M, Korth-Bradley J, Taylor C, Thomas M, Maniatis A, et al.
J Endocr Soc
. 2025 Jan;
9(2):bvaf001.
PMID: 39872400
Context: In patients with GH deficiency (GHD) receiving GH treatment, IGF-1 concentrations are used by physicians to monitor treatment safety and efficacy and guide dosing decisions. Somatrogon is a long-acting...
4.
Deal C, Steelman J, Vlachopapadopoulou E, Stawerska R, Silverman L, Phillip M, et al.
Ther Adv Endocrinol Metab
. 2024 Nov;
15:20420188241277404.
PMID: 39526285
• The efficacy of weekly injections was no different from that of daily injections to treat children who don't make enough growth to grow adequately. ○ Efficacy refers to how...
5.
Manners A, Korth-Bradley J, Wajnrajch M
Clin Pharmacol Drug Dev
. 2024 Jun;
13(10):1108-1114.
PMID: 38923773
Somatrogon-ghla is a long-acting, recombinant human growth hormone approved for the treatment of pediatric patients with growth hormone deficiency. Forty-nine healthy, adult males were enrolled in a randomized, crossover study...
6.
Gomez R, Khadilkar V, Shembalkar J, Chu D, Ko C, Wajnrajch M, et al.
J Pediatr Endocrinol Metab
. 2024 May;
37(6):525-531.
PMID: 38717038
Objectives: Somatrogon is a long-acting recombinant human growth hormone used to treat patients with paediatric growth hormone deficiency (pGHD). This global phase 3 study compared the efficacy and safety of...
7.
Geffner M, Ranke M, Wajnrajch M
Ann Pediatr Endocrinol Metab
. 2024 Mar;
29(1):3-11.
PMID: 38461800
The Kabi International Growth Study (KIGS) was first established in 1987 and is the largest pharmaco-epidemiological study of recombinant human growth hormone (rhGH). KIGS is aimed at evaluating long-term safety...
8.
Maghnie M, Ranke M, Geffner M, Vlachopapadopoulou E, Ibanez L, Carlsson M, et al.
J Clin Endocrinol Metab
. 2023 Feb;
108(6):e356-e357.
PMID: 36721915
No abstract available.
9.
Loftus J, Wogen J, Oliveri D, Benjumea D, Jhingran P, Chen Y, et al.
Front Endocrinol (Lausanne)
. 2022 Nov;
13:1014743.
PMID: 36407317
Background: Children with growth hormone deficiency (GHD) are treated with daily somatropin injections; however, poor treatment persistence and adherence have been recognized previously and have been shown to negatively impact...
10.
Maghnie M, Ranke M, Geffner M, Vlachopapadopoulou E, Ibanez L, Carlsson M, et al.
J Clin Endocrinol Metab
. 2022 Sep;
107(12):3287-3301.
PMID: 36102184
Context: The Kabi/Pfizer International Growth Database (KIGS) is a large, international database (1987-2012) of children treated with recombinant human growth hormone (rhGH) in real-world settings. Objective: This work aimed to...